MEGAResFrom MEG, the Microbial Ecology Group

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CME

The CME genes encode Ambler class A beta-lactamases. The cme genes (note the lack of capitalization) are also a part of the cmeABC multi-drug efflux system, which is under negative regulation of CmeR.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC89619/,http://www.sciencedirect.com/science/article/pii/S0006291X14009711

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Other Groups in Class A betalactamases

Sequences

Download Sequences

>>MEG_1735|Drugs|betalactams|Class_A_betalactamases|CME
atgaaaaaaattatactcctatttatcttgacaagccagttggtgcttgctcaacatacttcaatattaaatgatataaa
tgctgttaccaaagacaagaaagccacagtagctgtttctgttttggggatagaaaatgattttcagtttagtaacgcca
atggtaatttgaaaatgccgatgctgagtgtttttaaatttcatattgcattggcggttctaaatcaggtagacaaaggt
aaccttaccttggatcagaaaatactgattaaaaaatcggatctattagaaaatacatggtcaccacttcgtgagaagta
tccggatggaaatgtagaacttcctttaagcgaaattattacttatactgtagcccaaagtgacaacaacggatgcgaca
tactattaaggctaattggcgggactaaaactgttcagaaattaatggatgtgaatggtgtaaaaaactttcagataaaa
tataatgaggaagaaatgcataaaaatgatgtaaaaactctttatgcaaattacacaactacagcatctatggtaaaaac
tctgaaagcgttctataaaggaatgtttttatcaaaaagatccacaatttttctaatggatattatgactaaaaccaata
ccggaatgtcaaagcttccgggcttgctgccaaaagttagaatggccagaaaaacaggttcttcgggtaaaatgaaaaac
ggattaacgattgctgagaacgattcaggaattgtaactttagcaaatggtaaacattatgcaattgcagtatttgtaaa
ggactctatggaaggtgaggaagtcaattgtggaatcattgcccaggtctcgaaaattgtctgggatgctttaaataaaa
aaaataaaccctaa

>>MEG_1736|Drugs|betalactams|Class_A_betalactamases|CME
ATGAAAAAAATTATACTCCTATTTATCTTGACAAGCCAGTTGGTGCTTGCTCAACATACTTCAATATTAAATGATATAAA
TGCTGTTACCAAAGACAAGAAAGCCACAGTAGCTGTTTCTGTTTTGGGGATAGAAAATGATTTTCAGTTTAGTAACGCCA
ATGGTAATTTGAAAATGCCGATGCTGAGTGTTTTTAAATTTCATATTGCATTGGCGGTTCTAAATCAGGTAGACAAAGGT
AACCTTACCTTGGATCAGAAAATACTGATTAAAAAATCGGATCTATTAGAAAATACATGGTCACCACTTCGTGAGAAGTA
TCCGGATGGAAATGTAGAACTTCCTTTAAGCGAAATTATTACTTATACCGTAGCCCAAAGTGACAACAACGGATGCGACA
TACTATTAAGGCTAATTGGCGGGACTAAAACTGTTCAGAAATTAATGGATGTGAATGGTATAAAAAACTTTCAGATAAAA
TATAATGAGGAAGAAATGCATAAAAATGATGTAAAAACTCTTTATGCAAATTACACGACCACAGCATCTATGGTAAAAAC
TCTGAAAGCGTTCTATAAAGGAATGTTTTTATCAAAAAGATCCACAATTTTTCTAATGGATATTATGACTAAAACCAATA
CCGGAATGTCAAAGCTTCCGGGCTTGCTGCCAAAAGTTAGAATGGCCAGAAAAACAGGTTCTTCGGGTAAAATGAAAAAC
GGATTAACGATTGCTGAGAACGATTCAGGAATTGTAACTTTAGCAAATGGTAAACATTATGCAATTGCAGTATTTGTAAA
GGACTCTATGGAAAGTGAGGAAGTCAATTGTGGAATGATTGCCCAGGTCTCGAAAATTGTCTGGGATGCTTTAAATAAAA
AAAAATAA