MEGAResFrom MEG, the Microbial Ecology Group

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Sulfonamide-resistant dihydropteroate synthases

Resistance to sulfonamides primarily occurs via mutation in the folP gene that reduces binding affinity of the sulfonamides, or by plasmid or chromosomally encoded sul genes that encode forms of dihydropteroate synthase that are not inhibited by sulfonamides.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC440870/

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Other Mechanisms in Sulfonamides

Groups

Sequences

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