The fluoroquinolone class of antibiotics target the bacterial DNA topoisomerases II (gyrase) and IV, converting them into a product that is toxic to the bacterial cell. Common drugs in this class include ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, etc.
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- Fluoroquinolone ABC efflux pump
- Fluoroquinolone resistance phosphotransferase
- Fluoroquinolone-resistant DNA topoisomerases
- Quinolone active efflux
- Quinolone resistance protein Qnr