MEGAResFrom MEG, the Microbial Ecology Group

LHK

The LHK group of genes confer resistance to betalactams through the mechanism, Class A betalactamases.

References

    Other Groups in Class A betalactamases

    Sequences

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    >>MEG_3580|Drugs|betalactams|Class_A_betalactamases|LHK
    atgaaaaaacggattaccccattttcccgatttgcatcaaaaggcctttccgcctgtagcgcaggcatgttgctggtgac
    ggtggcacatgccgccaatacggcagcagcaccagccggtgtggatgccatggtccaaaccgtgatgcaggcacaccaga
    ttccgggcatggccattgccatcatccagccaggaaagaccacttatcacaattatggtgtcgcctcccgcgaaaccggc
    cagccggtccgggaaaccaccctgtttgaaatcggctccctttccaaaccgtttactgcactggtcgcccagcgggctga
    aaccgaaggccggattgacctgtctgcaccggccagccgctacgttaccgccctgcggggcagtgcattcgaccggatca
    ccctcaggcagctcggtacttatagtgcaggcggattaccgctccagtttcctgacaatgtcactaccccggcagatgta
    ctggcttattaccgccattggcaacctgtccatccggcaggtagcacccggctgtattccaatccgagcattggcctgat
    ggggctggctgccagtcaggcaaccggagagtcctttgccggcctgctcgggacaacggtgctgcaacccctcggcatga
    actcgacctatctgcaagtgcccccggaggcccgttcacgttatgccatgggttataccgccgccgggaaaccggtcagg
    gtcaaccccggtccgctggatgaggaaacctacggcgtcaagtccacaaccgcagacatggccggatttttactggcgca
    tatggaccctgcgcgcagcaaaggtgcattgcggtcggcattacagcaaacacgtgtaccggtttattgtgccggacaga
    cccggcaaggactgggctgggaaagttatcaagactggaaaaacctcgacgtgctgctggcgggaaattcaaatcaaatg
    gtgtttgaaccgcagccggtaaaagcctgtcttgccggcaccatgaatgagcctgatgtgtgggtcaacaagaccggttc
    tactgcgggattcggcgcttatgccgtattcctgcctgcccgacagaccggcattgtcatcctggccaaccgtaattacc
    cgattgcagaccgtatccggctcgctcacgggattttgaccgcattgcactga

    >>MEG_3581|Drugs|betalactams|Class_A_betalactamases|LHK
    atgaaaaaacggattaccccattttcccgatttgcatcaaaaggcctttccgcctgtagcgcaggcatgttgctggtgac
    ggtggcacatgccgccaatacggcagcagcgccagccggcatggatgccatggtccaaaccgtgatgcaggcacaccaga
    ttccgggcatggccattgccatcatccagccaggaaagaccacttatcacaattatggtatcgcctcccgcgaaaccggc
    cagccggtccgggaaaccaccctgtttgaaatcggctccctttccaaaccgtttactgcactggtcgcccagcgggctga
    aaccgaaggccggattgacctgtctgcaccggccagccgctacgttaccgccctgcggggcagtgcattcgaccggatca
    ccctcaggcagctcggtacttatagtgcaggcgaattgccgctccagtttcctgacaatgtcaccaccccggcagacgtg
    ctggcttattaccgccattggcaacctgtccatccggcaggtaccacccggctgtattccaatccgagcattggcctgat
    ggggctggctgccagtcaggcaaccggagagtcctttgccggcctgctcgggacaacggtgctgcaacccctcggcatga
    actcgacctatctgcaagtgcctccggaggcccgttcacgttatgccatgggttataccgccgccgggaaaccggtcagg
    gtcagccccggtccgctggatgaggaaacctacggcgtcaagtccacaaccgcagacatggccggatttttattggcgca
    tatggaccctgcgcgcagcaaaggtgcattgcggtcggcattacagcaaacacgtgtaccggtttattgcgccggacaga
    cccggcaaggactgggctgggaaagttatcaagactggaaaaacctcgacgtgctgctggcgggaaattcaaatcaaatg
    gtgtttgaaccgcagccggtaaaagcctgtcttgccggcacctcgaatgagcccgacgtatgggtcaacaagacaggttc
    tactgcgggattcggcgcttatgccgtattcctgcctgcccgacaggccggcattgtcatcctagccaaccgtaattacc
    cgattgcagaccgtatccggctcgctcacggaattttgaccgcattgcactga

    >>MEG_3582|Drugs|betalactams|Class_A_betalactamases|LHK
    atgaaaaaacggattaccccattttcccgatttgcatcaaaaggcctttccgcctgtagcgcaggcatgttgctggtgac
    ggtggcacatgccgccaatacggcagcagcgccagccggcatggatgccatggtccaaaccgtgatgcaggcacaccaga
    ttccgggcatggccattgccatcatccagcctggcaagaccacttatcacaattatggtgtcgcctcccgcgaaaccggc
    cagccggtccgggaaaccaccctgtttgaaatcggctccctttccaaaccgtttactgcactggtcgcccagcgggctga
    aaccgaaggccggattgacctgtctgcaccggccagccgctacgttaccgccctgcggggcagtgcattcgaccggatca
    ccctcaggcagctcggtacttatagcgcaggcggattaccgctccagtttcctgacaatgtcaccaccccggcagatgtg
    ctggcttattaccggcattggcaacctgtccatccggcaggcaccacccggctgtattccaatccgagcattggcctgat
    ggggctggctgccagcctggcaaccggagagtcctttgccggcctgctcgggacaacggtgctgcaacccctcggcatga
    actcgacctatctgcaagtgcccccggaggcccgttcacgttatgccatgggttataccgccgccgggaaaccggtcagg
    gtcaaccccggtccgctggatgaggaaacctacggcgtcaagtccacaaccgcagacatggtcggatttttattggcgca
    tatggaccctgcacgcagcaaaggtgcattgcggtcggcattacagcaaacacgtgtaccggtttattgcgccggacaga
    cccggcaaggactgggctgggaaagttatcaagactggaaaaacctcgacatgctgctggcgggaaattcaaatcaaatg
    gtgtttgaaccgcagctggtaaaagcctgtcctgccggcaccatgaatgagcccaatgtgtgggtcaacaagaccggttc
    tactgcgggattcggcgcttatgccgtattcctgcctgcccgacaaaccggcattgtcatcctggccaaccgtaattacc
    cgattgcagaccgtatccggctcgctcacggaattttgaccgcattgcactga

    >>MEG_3583|Drugs|betalactams|Class_A_betalactamases|LHK
    atgaaaaaacggattaccccattttcccgatttgcatcaaaaggccttttcgcctgtagcgcaggcatgttgctggtgac
    ggtggcacatgccgccaatacggcagcagcgccagccggtgtggatgccatggtccaaaccgtgatgcaggcacaccaga
    ttccgggcatggccattgccatcatccagccaggcaagacctcttatcacaattatggtgtcgcctcccgcgaaaccggc
    cagccggtccgggaaaccactctgtttgaaatcggctccctttccaaaccgtttactgcactggtcgcccagcgggccga
    aaccgaaggccggattgacctgtctgcaccggccagccgctacgttgccgccctgcgaggcagtgcattcgaccggatca
    ccctcaggcagctcggtacttatagcgcaggcggattaccgctccagtttcctgacaatgtcaccaccccggcagacatg
    ctggcttattaccagcattggcaacctgtccatccggcaggtaccacccggctgtattccaatccgagcattggcctgat
    ggggctggctgccagtcaggcaaccggagagtcctttgccggcctgctcgggacaacggtgctgcaacctctcggcatga
    actcgacctatctgcaagtgcccccggaggcccgttcacgttatgccatgggttataccgccgccgggaaaccggtcagg
    gtcagccccggtccgctggatgaggaaacctacggcatcaagtccacaaccgcagacatggccggatttttactggcgca
    tatggaccctgcgcgcagcaaagatgcattgcggtcggcattacagcaacgtgcaccggtttattgcgccggacagaccc
    ggcaaggactgggctgggaaagttatcaagactggaaaaacctagacgtgctgctggcgggaaattcaaatcaaatggtg
    tttgaaccgcagccggtaaaagcctgtcctgccggcaccatgaatgagcccgatgtgtgggtcaacaagaccggttctac
    tgcgggattcggcgcttatgccgtattcctgcctgcccgacagaccggcattgtcatcctggccaaccgtaattacccga
    ttacagaccgtatccggctcgctcacgggattttgaccgcattgcactag

    >>MEG_3584|Drugs|betalactams|Class_A_betalactamases|LHK
    atgaaaaaacggattaccccattttcccgatttgcatcaaaaggccttttcgcctgtagcgcaggcatgttgctggtgac
    ggtggcacatgccgccaatatggcagcagcaccagccggcatggatgccatggtacaaaccgtgatgcaggcacaccaga
    ttccgggcatggccattgccatcatccagccaggaaagaccacttatcacaattatggtgtcgcctcccgcgaaaccggc
    cagccggtccgggaaaccaccctgtttgaaatcggctccctttccaaaccgtttactgcactggtcgcccagcgggctga
    aaccgaaggccggattgacctgtctgcaccggccagccgctacgttaccgccctgcggggcagtgcattcgaccggatca
    ccctcaggcagctcggtacttatagtgcaggcggattaccgctccagtttcctgacaatgtcactaccccggcagatgta
    ctggcttattaccgccattggcaacctgtccatccggcaggtagcacccggctgtattccaatccgagcattggcctgat
    ggggctggctgccagtcaggcaaccggagagtcctttgccggcctgctcgggacaacggtgctgcaacccctcggcatga
    actcgacctatctgcaagtgcccccggaggcccgttcacgttatgccatgggttataccgccgccgggaaaccggtcagg
    gtcaaccccggtccgctggatgaggaaacctacggcgtcaagtccacaaccgcagacatggccggatttttactggcgca
    tatggaccctgcgcgcagcaaaggtgcattgcggtcggcattacagcaaacacgtgtaccggtttattgtgccggacaga
    cccggcaaggactgggctgggaaagttatcaagactggaaaaacctcgacgtgctgctggcgggaaattcaaatcaaatg
    gtgtttgaaccgcagccggtaaaagcctgtcttgccggcaccatgaatgagcctgatgtgtgggtcaacaagaccggttc
    tactgcgggattcggcgcttatgccgtattcctgcctgcccgacagaccggcattgtcatcctggccaaccgtaattacc
    cgattgcagaccgtatccggctcgctcacggaattttgaccgcattgcactga

    >>MEG_3585|Drugs|betalactams|Class_A_betalactamases|LHK
    atgaaaaaacggattaccccattttcccgctttgcatcaaaaggccttttcgcctgtagcacaggcatgttgctggtgac
    ggtggcacatgctgccaatacagcagcagccggcatggatgccatgatacaaaccgtgatgcaggcacaccagattccgg
    gcatggccattgccatcatccagtcaggcaagaccacttatcacaattatggtgtcgcctcccgcgaaaccggccagccg
    gtccgggaaaccaccctgtttgaaatcggctccctttccaaaccgtttactgcactgatcgcccagcgggctgaaaccga
    aggccggattgacctgtctgcaccggccagccgctacgttaccgccctgcggggcagtgcattcgaccggatcaccctca
    ggcagctcggtacttatagcgcaggcggattaccgctccagtttcctgacaatgtcaccaccccggcagatgtgctggct
    tattaccggcattggcaacctgtccatccggcaggcaccacccggctgtattccaatccgagcattggcctgatggggct
    ggctgccagcctggcaaccggagagtcctttgccggcctgctcgggacaacggtgctgcaacccctcggcatgaactcga
    cctatctgcaaatgcccccggaggcccgttcacgttatgccatgggttataccgccgccgggaaaccggtcagggtcaac
    cccggtccgctggatgaggaaacctacggcgtcaagtccacaaccgcagacatggccggatttttattggcgcatatgga
    ccctgcacgcagcaaaggtgcattgcggtcggcattacagcaaacacgtgtaccggtttattgcgccggacagacccggc
    aaggactgggctgggaaagttatcaagactggaaaaacctcgacgtgctgctggcgggaaattcaaatcaaatggtgttt
    gagccgcagccggtgaaagcctgtcctgccggcaccatgaatgagcccgatgtgtgggtcaacaagaccggttctactgc
    gggattcggcgcttatgccgtattcctgcctgcccgacaaaccggcattgtcatcctggccaaccgtaattacccgattg
    cagaccgtatccggctcgctcacggaattttgaccgcattgcactga