MEGAResFrom MEG, the Microbial Ecology Group

DFRD

The dfr genes in this category of resistance encode a dihydrofolate reductase enzyme that is less vulernable to trimethoprim than wild type.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/6985448

Other Groups in Dihydrofolate reductase

Sequences

Download Sequences

>>MEG_2574|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRD
ATGTGGTCATTCTTGAAAATTTCTTTAATTGTTGCGATGGATAAGAAAAGAGTAATCGGCAAGGATAACGACATTCCATG
GAGAATTTCTAGTGATTGGGAATATGTAAAAAACACTACAAAAGGACATGCAATCATATTAGGTAGAAAGAACCTTCAAT
CAATCGGAAGGGCTTTACCTGACAGAAGAAATATTATTTTGACTAGAGATAAAAACTTTAACTTTAAGGATTGTGAAATT
GCCCATTCAATAGAAGCTGCATTTAAGTTATGCGAAAATGAAGAAGAGGTTTTCATTTTCGGGGGAGAACAGATATATGT
TATGTTCTTGCCTTATGTCGAGAAAATGTACGTTACAAAAATTCATCATGAATTCGAAGGAGATACATTTTTTCCAGTAG
TTAATTTTGACGATTGGAAAGAAGTATCTGTTGAAAAAGGAATAAAAGATGAAAAGAATCCTTACGATTATTATTTTCAT
ATATATGAGAGAATTCGTTAA

>>MEG_2575|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRD
TTGAAAATTTCTTTAATTGTTGCGATGGATAAGAAAAGAGTAATCGGCAAGGATAACGACATTCCATGGAGAATTTCTAG
TGATTGGGAATATGTAAAAAACACTACAAAAGGACATGCAATCATATTAGGTAGAAAGAACCTTCAATCAATCGGAAGGG
CTTTACCTGACAGAAGAAATATTATTTTGACTAGAGATAAAAACTTTAACTTTAAGGATTGTGAAATTGCCCATTCAATA
GAAGCTGCATTTAAGTTATGCGAAAATGAAGAAGAGGTTTTCATTTTCGGGGGAGAACAGATATATGTTATGTTCTTGCC
TTATGTCGAGAAAATGTACGTTACAAAAATTCATCATGAATTCGAAGGAGATACATTTTTTCCAGTAGTTAATTTTGACG
ATTGGAAAGAAGTATCTGTTGAAAAAGGAATAAAAGATGAAAAGAATCCTTACGATTATTATTTTCATATATATGAGAGA
ATTCGTTAA

>>MEG_2576|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRD
GTAAAATAGGTTAAAAAGGATGTGGTCATTCTTGAAAATTTCTTTAATTGTTGCGATGGATAAGAAAAGAGTAATCGGCA
AGGATAACGACATTCCATGGAGAATTTCTAGTGATTGGGAATATGTAAAAAACACTACAAAAGGACATGCAATCATATTA
GGTAGAAAGAACCTTCAATCAATCGGAAGGGCTTTACCTGACAGAAGAAATATTATTTTGACTAGAGATAAAAACTTTAA
CTTTAAGGATTGTGAAATTGCCCATTCAATAGAAGCTGCATTTAAGTTATGCGAAAATGAAGAAGAGGTTTTCATTTTCG
GGGGAGAACAGATATATGTTATGTTCTTGCCTTATGTCGAGAAAATGTACGTTACAAAAATTCATCATGAATTCGAAGGA
GATACATTTTTTCCAGTAGTTAATTTTGACGATTGGAAAGAAGTATCTGTTGAAAAAGGAATAAAAGATGAAAAGAATCC
TTACGATTATTATTTTCATATATATGAGAGAATTCGTTAA