MEGAResFrom MEG, the Microbial Ecology Group

DFRD

The dfr genes in this category of resistance encode a dihydrofolate reductase enzyme that is less vulernable to trimethoprim than wild type.

References

Other Groups in Dihydrofolate reductase

Sequences

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>Tmt|DfrD|Z50141|94-582|489|Trimethoprim|Dihydrofolate_reductase|DFRD
ATGTGGTCATTCTTGAAAATTTCTTTAATTGTTGCGATGGATAAGAAAAGAGTAATCGGCAAGGATAACGACATTCCATG
GAGAATTTCTAGTGATTGGGAATATGTAAAAAACACTACAAAAGGACATGCAATCATATTAGGTAGAAAGAACCTTCAAT
CAATCGGAAGGGCTTTACCTGACAGAAGAAATATTATTTTGACTAGAGATAAAAACTTTAACTTTAAGGATTGTGAAATT
GCCCATTCAATAGAAGCTGCATTTAAGTTATGCGAAAATGAAGAAGAGGTTTTCATTTTCGGGGGAGAACAGATATATGT
TATGTTCTTGCCTTATGTCGAGAAAATGTACGTTACAAAAATTCATCATGAATTCGAAGGAGATACATTTTTTCCAGTAG
TTAATTTTGACGATTGGAAAGAAGTATCTGTTGAAAAAGGAATAAAAGATGAAAAGAATCCTTACGATTATTATTTTCAT
ATATATGAGAGAATTCGTTAA

>Tmt|U43152.1|gene1|Trimethoprim|Dihydrofolate_reductase|DFRD
GTAAAATAGGTTAAAAAGGATGTGGTCATTCTTGAAAATTTCTTTAATTGTTGCGATGGATAAGAAAAGAGTAATCGGCA
AGGATAACGACATTCCATGGAGAATTTCTAGTGATTGGGAATATGTAAAAAACACTACAAAAGGACATGCAATCATATTA
GGTAGAAAGAACCTTCAATCAATCGGAAGGGCTTTACCTGACAGAAGAAATATTATTTTGACTAGAGATAAAAACTTTAA
CTTTAAGGATTGTGAAATTGCCCATTCAATAGAAGCTGCATTTAAGTTATGCGAAAATGAAGAAGAGGTTTTCATTTTCG
GGGGAGAACAGATATATGTTATGTTCTTGCCTTATGTCGAGAAAATGTACGTTACAAAAATTCATCATGAATTCGAAGGA
GATACATTTTTTCCAGTAGTTAATTTTGACGATTGGAAAGAAGTATCTGTTGAAAAAGGAATAAAAGATGAAAAGAATCC
TTACGATTATTATTTTCATATATATGAGAGAATTCGTTAA