MEGAResFrom MEG, the Microbial Ecology Group

ERMS

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

Other Groups in 23S rRNA methyltransferases

Sequences

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>CARD|phgb|M19269|459-1419|ARO:3001304|ErmS|MLS|23S_rRNA_methyltransferases|ERMS
GTGGCCCGTGCACCCCGATCGCCCCACCCTGCCCGCTCGCGGGAGACCTCCCGCGCCCACCCGCCGTACGGCACCCGTGC
GGATCGCGCCCCCGGCCGTGGCCGTGACCGTGACCGCAGCCCCGACAGCCCCGGCAACACCAGCAGCCGCGACGGCGGCC
GCAGCCCCGACCGCGCGCGGCGCGAGCTCTCGCAGAACTTCCTCGCCCGCCGGGCCGTCGCCGAGCGCGTCGCGCGCCTG
GTCCGGCCGGCCCCCGGCGGTCTGTTGCTGGAGGTCGGCGCCGGGCGCGGCGTCCTGACCGAGGCGCTGGCCCCGTACTG
CGGGCGGCTGGTCGCCCACGAGATCGACCCCCGTCTGCTGCCGGCGCTGCGCGACCGGTTCGGCGGCCCGCACCATGCCC
ATGTGCGGATCAGCGGCGGCGACTTCCTGGCAGCCCCCGTCCCCCGTGAGCCGTTCGCCCTCGCGGGGAACATCCCCTAC
TCCCGGACCGCGGGAATCGTGGACTGGGCGCTGCGGGCGCGCACGCTCACCTCGGCGACCTTCGTCACCCAGCTCGAGTA
CGCCCGCAAGCGGACCGGCGACTATGGACGCTGGAGCCTGCTGACGGTGCGGACCTGGCCCCGCCACGAGTGGCGGCTGC
TCGGCAGGGTCTCCCGCCGGGAGTTCCGGCCGGTGCCCCGCGTGGACTCGGGCATCCTCCGGATCGAGCGGCGCGAGCGG
CCCCTGCTGCCGTCCGCCGCCCTCGGCGACTACCACCGCATGGTGGAGCTGGGTTTCTCCGGCGTGGGCGGATCGCTGTA
CGCATCGCTGCGCCGGGCCCACCGGGCGGGGCCGCTCGACGCCGCGTTCCGTGCCGCGCGGCTGGACCGCTCCGTCGTCG
TCGCGTATGTCACACCGGAGCAGTGGCTCACGGTCTTCCGCACGTTGCGGCCCGTCCGCAGCCGACCGGCCGGACGGTGA
A