MEGAResFrom MEG, the Microbial Ecology Group

VanB-type accessory protein

The vancomycin resistance gene clusters contain three general categories of genes, the core resistance proteins (VanHAX), the accessory proteins (VanJKWYZ and MurF2), and the sensor-regulator genes (VanRS). The accessory proteins are not essential for resistance but are known to enhance resistance in some bacteria. Other accessory genes, such as vanW, have unknown function at this time. The VanB resistance cluster is similar to VanA in that it is acquired and inducible, but it differs on sequence identity. Its terminal product is D-ala-D-lac.

References

Other Mechanisms in Glycopeptides

Groups

Sequences

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