MEGAResFrom MEG, the Microbial Ecology Group

Ribosomal zinc-binding protein

Though the exact mechanism is unknown, the protein encoded by fusB is known to bind Elongation Factor G (EF-G), which is the target of fusidic acid. This suggests that the product of fusB in some way prevents the binding of EF-G by fusidic acid, therefore causing resistance.



Other Mechanisms in Fusidic acid



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