MEGAResFrom MEG, the Microbial Ecology Group

Ribosomal zinc-binding protein

Though the exact mechanism is unknown, the protein encoded by fusB is known to bind Elongation Factor G (EF-G), which is the target of fusidic acid. This suggests that the product of fusB in some way prevents the binding of EF-G by fusidic acid, therefore causing resistance.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/16390458

Other Mechanisms in Fusidic acid

Groups

Sequences

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