MEGAResFrom MEG, the Microbial Ecology Group

Elfamycins

The elfamycin class of antibiotics are characterized by their common target: Elongation Factor Tu (EF-Tu). EF-Tu is an integral part of protein synthesis, and inhibition of EF-Tu disrupts protein synthesis in various ways. The four main drugs in this class of antibiotics are kirromycin, enacyloxin, pulvomycin, and GE2270A.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/16876786

Mechanisms

Sequences

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