Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /home/meglabuser/megares.meglab.org/vendor/doctrine/orm/lib/Doctrine/ORM/UnitOfWork.php on line 2640
MEGARes
MEGAResFrom MEG, the Microbial Ecology Group

betalactams

The core structure of beta-lactam antibiotics is the beta-lactam nucleus, or 6-aminopenicillanic acid (7-aminocephalosporanic acid for the cephalosporins). Side chains are added to this core structure to produce novel beta-lactam antibiotics. The mechanism of action of beta-lactams is the inhibition of the penicillin binding proteins (PBPs) that cross-link components of the bacterial cell wall, a function necessary for bacterial proliferation. There are many beta-lactam antibiotics, but common drug classes within the beta-lactams include the penams (penicillin derivatives), cephalosporins, carbapenems, and monobactams.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894812/pdf/nihms156704.pdf

Mechanisms


Deprecated: The behavior of unparenthesized expressions containing both '.' and '+'/'-' will change in PHP 8: '+'/'-' will take a higher precedence in /home/meglabuser/megares.meglab.org/src/Sequence.php on line 169

Sequences

Download Sequences