Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /home/meglabuser/megares.meglab.org/vendor/doctrine/orm/lib/Doctrine/ORM/UnitOfWork.php on line 2640
MEGAResFrom MEG, the Microbial Ecology Group


The sulfonamides are analogues of p-aminobenzoic acid (PABA) and are competitive inhibitors of dihydropteroate synthase, an enzyme required for proliferation in some bacteria. Because they inhibit a required product, folic acid, they are bacteriostatic. Resistance to sulfonamides primarily occurs via mutation in the folP gene that reduces binding affinity of the sulfonamides, or by plasmid or chromosomally encoded sul genes that encode forms of dihydropteroate synthase that are not inhibited by sulfonamides.


  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC440870/


Deprecated: The behavior of unparenthesized expressions containing both '.' and '+'/'-' will change in PHP 8: '+'/'-' will take a higher precedence in /home/meglabuser/megares.meglab.org/src/Sequence.php on line 169


Download Sequences