MEGAResFrom MEG, the Microbial Ecology Group

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VGBA

The vgb genes encode lyases that catalyze an elimination reaction across the streptogramin B ester bond. This inactivates the antibiotic molecule.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/11467949

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Other Groups in Streptogramin B ester bond cleavage

Sequences

Download Sequences

>>MEG_7691|Drugs|MLS|Streptogramin_B_ester_bond_cleavage|VGBA
atggaatttaaattacaagaattaaatcttactaaccaagatacaggaccatatggtataaccgtttcagataaggggaa
agtttggattacacaacataaagcaaatatgataagttgcatcaatttagatggaaaaattacagagtacccactaccga
caccagatgcaaaagtcatgtgtttaactatatcctcagatggggaagtttggtttactgagaatgcagcaaacaaaata
gggaggattacaaaaaaagggattattaaggaatatacattgcctaacccagattcagcaccctacggtattacagaagg
accaaatggagatatatggtttacagaaatgaatggcaaccgtattggacgtattacggacgacggtaaaattcgtgaat
acgagctgcctaataaaggatcttacccttcttttatcactttgggttctgataatgccctgtggttcacagaaaatcaa
aataatgctattggtagaattacagaaagtggggatattacagagtttaaaattcctacacctgcatcaggaccagttgg
tattacaaaggggaacgacgatgctttatggtttgtggaaattatcggtaataagatagggcgaataactcctctggggg
aaattaccgaattcaaaattccaacgccaaacgctcgacctcatgcaattactgctggagcaggaattgatttatggttt
actgaatggggggctaataaaataggaaggctgacaagcaataatataattgaggaatacccaattcaaatcaaaagtgg
tgaaccacatggcatttgtttcgatggtgaaacaatttggtttgcaatggagtgtgacaagataggcaaattaactctca
ttaaggataatatggagtga

>>MEG_7692|Drugs|MLS|Streptogramin_B_ester_bond_cleavage|VGBA
ATGGAATTTAAATTACAAGAATTAAATCTTACTAACCAAGATACAGGACCATATGGTATAACCGTTTCAGATAAGGGGAA
AGTTTGGATTACACAACATAAAGCAAATATGATAAGTTGCATCAATTTAGATGGAAAAATTACAGAGTACCCACTACCGA
CACCAGATGCAAAAGTCATGTGTTTAACTATATCCTCAGATGGGGAAGTTTGGTTTACTGAGAATGCAGCAAACAAAATA
GGGAGGATTACAAAAAAAGGGATTATTAAGGAATATACATTGCCTAACCCAGATTCAGCACCCTACGGTATTACAGAAGG
ACCAAATGGAGATATATGGTTTACAGAAATGAATGGCAACCGTATTGGACGTATTACGGACGACGGTAAAATTCGTGAAT
ACGAGCTGCCTAATAAAGGATCTTACCCTTCTTTTATCACTTTGGGTTCTGATAATGCCCTGTGGTTCACAGAAAATCAA
AATAATGCTATTGGTAGAATTACAGAAAGTGGGGATATTACAGAGTTTAAAATTCCTACACCTGCATCAGGACCAGTTGG
TATTACAAAGGGGAACGACGATGCTTTATGGTTTGTGGAAATTATCGGTAATAAGATAGGGCGAATAACTCCTCTGGGGG
AAATTACCGAATTCAAAATTCCAACGCCAAACGCTCGACCTCATGCAATTACTGCTGGAGCAGGAATTGATTTATGGTTT
ACTGAATGGGGGGCTAATAAAATAGGAAGGCTGACAAGCAATAATATAATTGAGGAATACCCAATTCAAATCAAAAGTGC
TGAACCACATGGCATTTGTTTCGATGGTGAAACAATTTGGTTTGCAATGGAGTGTGACAAGATAGGCAAATTAACTCTCA
TTAAGGATAATATGGAGTGA