MEGAResFrom MEG, the Microbial Ecology Group

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MPHB

The mph genes encode macrolide phosphotransferases that have been shown to confer resistance to erythromycin by inactivation of the antibiotic molecule via phosphorylation.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC94651/

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Other Groups in Macrolide phosphotransferases

Sequences

Download Sequences

>>MEG_4031|Drugs|MLS|Macrolide_phosphotransferases|MPHB
atgagtaaagatattaaacaagtaatcgagatagcaaaaaaacacaatctttttctaaaagaagaaacgatacagtttaa
tgaatcagggcttgattttcaagctgtttttgcacaagataataatggaattgattgggttctaagattgcctagacggg
aagatgtgatgcctagaacaaaggtagaaaaacaagctttggatttggtaaataagtacgctatatcctttcaggcacca
aactggatcatttacacagaggaactaatagcttataaaaagttagatggtgtgccagcaggtacgatagatcataacat
aggtaactatatttgggagatagacataaataatgttccagaattatttcacaagtcgctaggcagggtgttagcagagc
ttcatagcatacctagtaataaagccgcagcgcttgatcttgtagtacacacaccagaagaagcaagaatgtcaatgaag
cagcgtatggatgcagtaagagcaaagttcggagtaggtgagaatctatggaacagatggcaagcgtggttgaatgatga
tgatatgtggcctaagaaaactggactgattcatggagatgtacatgccggacatactatgattgataaggatgccaatg
tgactggattaatcgattggactgaagcgaaggttacagatgtttcgcatgactttattttcaactatagagcttttggg
gaagaagggttagaagctttaattctcgcttataaggaaattggtggatattactggcctaaaatgaaagagcatattat
cgaacttaatgcagcatacccagtttcaatcgctgagtttgcattagtgtctggaattgaggaatatgagcagatggcaa
aggaagcattggaagtacaaggttcgtaa

>>MEG_4032|Drugs|MLS|Macrolide_phosphotransferases|MPHB
ttgaacaaacagaaagcggtagaaatagcaagaaagtatggtttggaagttaaagatgagtccatcatattcaacgagtc
cggtttagattttctggttgcttatgcagaagacgataaaggcgaagaatgggtgctaaggtttccgagacgggacgatg
tgatgccaaggacgatagtggagaagaaagcactggatcttgtaaataaatatgccacttttcaggttccagtctggtcg
gtttatgaaggcgatctaatagcttataaaaagttaatcggagtgccagcaggcacgattgatccggagattcaaaacta
tgtgtgggagatggattatgaaaatgtgcctgaacaatttcaccagacattagccaaagcgttggcttcgctacacacag
ttccgaaaacagaggctcttaaagtaggcctgtttgtccagacagcagaagaggcaagaaaatcgatgattgagcgtatg
aaaaaggttaaagcgaagtttggcgtaggcgaatccttatggaaccgctggcaggcctgggtaaaaaatgaggaattgtg
gcctcagagaacaggtctgattcatggggatgttcatgctggccacacgatgattgataaagatgctaacttaacaggtt
ttatcgactggaccgaagcaaaagtaacggatgtatcaaatgactttgttttccagtaccgggtattcggggaggcagcc
ctggagaaactgatcaactattaccggcaagcaggtgggatttactggcctgccatgaaagagcacgtcattgaacttaa
tgcggcataccctgttgcgatagctgagtttgcgattatctcaggcttggaagaatatgagcagatggcgaaagaaacat
tggaagtgaatgaccgctag

>>MEG_4033|Drugs|MLS|Macrolide_phosphotransferases|MPHB
ATGCCGACGATCCACGTCTCAATAGTATCGTTCAGCAACTCTTTCGCGTACTCCGGGGGTTACATGACTGAAGAGTGCGG
GGAAATTGTTTTCTGGACGCTGCGAAAAAAGTTTGTCGCCAGTAGCGACGAGATGCCGGAACACAGCTCCCAGGTAATGT
ATTACTCGCTGGCTATCGGTCATCACGTTGGCGTGATTGATTGTCTGAATGTCACCTTCCGCTGCCCACTGACGGAATAC
GAAGATTGGCTTGCACTGGTCGAAGAGGAGCAAGCCCGACGTAAGATGCTGGGGGTGATGACTTTTGGTGAGATTGTTAT
TGACGCCAGCCACACCGCCCTGTTGACCCGGGCATTCGCGCCACTGGCAGATGACGCGACGTCTGTGTGGCAAGCGCGTA
GCATTCAATTCATTCATCTGTTGGATGAAATTGTGCTGGAACCGGCTATCTATCTGATGGCCAGAAAAATTGCGTGA