MEGAResFrom MEG, the Microbial Ecology Group

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MPH

The mph genes encode macrolide phosphotransferases that have been shown to confer resistance to erythromycin by inactivation of the antibiotic molecule via phosphorylation.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC94651/

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Other Groups in Macrolide phosphotransferases

Sequences

Download Sequences

>>MEG_4026|Drugs|MLS|Macrolide_phosphotransferases|MPH
TTGGAGGAAATAAAAATGAACACACTTAAAATTAAACAATTAGCAACTAAGGAAGGCCTAAATATCTTAGAAGATTCAAT
AAAAATCAATGAATCTGGTGTTGACTTTCAAGTAGCACACGCTAAAGAACAAAACGGAGATAAATGGATACTAAGAATTC
CTCGTAGACCAGAATCTATGAGACATGTCCTACAAGAAAAAAAGGCATTGGAAATCATAAAAAACCATGCAGGATTCCAA
GTTCCTGATTGGTCTATATTCACTGAAGACTTAATTGCCTATAAGCAACTAAGTGGCGTTCCTGCCGCCACTATTGATAT
AGAACAACAAGGATATATATGGAGCTTTAATGAAAAAAACGCACCATCTGAATACCATATTTCATTAGGAAAAGTTCTAG
CGAATTTACACTCATTACCTCAACAAGAATTTAATAATATCGGTATTGAAATTCTTACTGCTAATGAATTAAGAGCTTCT
ATGGAACAAAGGATGAATCGAGTGAAGGAACAATACTATGTCAATCAAAAATTATGGGATCGTTGGCAAGCATGGCTAAC
TGAAGATTCTTTTTGGCCATCTCATGTAGGAGTAACGCATGGGGATATACATCCAGGTCATATCCTGATTGATAAGAAAA
ATAATGTAACTGGCTTAATCGATTGGACAGAAGTAGGGATAGCTGATGTTTCTATAGATTTCACATCACATTATCTGCTC
TTTGGGAAAGATGGACTAACAAAGTTAATTAGCTCTTATGACAATGCTGGTGGTAAAACTTGGTCAAGAATGGATGAACA
TATTATCGAACTTCTAACAACAAGTAGTATCACTGTTGCTGAATATGCTCAAGTGTCAGGTTTGAAAGAGATGCATGAAG
CAGCTGTACACATGCTAGCAACTGAAAGTTAA

>>MEG_4027|Drugs|MLS|Macrolide_phosphotransferases|MPH
ATGAACGAATTTAAACGGCTTGCAAAAAATAAAGGATTAGATGTGTTAGAGAATAGCATTGTGGTAAATGAATCGGGTGT
TGATTTTCAAGTTGCTTATGCAAAAGATACGCTTGGTAGCAAGTGGATACTAAGAATTCCTCGAAGATTAGATTCGATGA
GGAGCGCCTTGAAAGAAAAGATGGCACTAGAAATTATGGAAGAACATGTGAGTTTTCAAGTTCCAAATTGGTCGATTTTT
GATGATGAACTAATTGCGTATAAGCAATTAGATGGTGTTCCGGTTGCAACAATTGATGTAGAGCAACAAGATTACATCTG
GAGTTTTGACAAAGAGAATACACCACAATCTTACTATCAGTCATTAGGTAAAGTGTTGGCAGAACTACACACATTACCAC
ATCGACACTTCAAAGAAATCGGTATCAAAACTCTATATGCTAGAGATTTAAAGAGTTCAATGAAGATACGGATGGAGAAG
GTGAGACAGAAGTATCATGTGAATTCAGAGCTATGGGAGCGTTGGCAAGAATGGTTGGCGAATGATTCGCTATGGCCATC
GCATGTAGGTGTAAGCCACGGGGATTTACACCCTGGCCACATACTAATAAATAAGAATTTTGAGGTCTCTGGTTTGATAG
ATTGGACAGAAATTAGTATTGCGGACACATCTGTGGATTTTCTATCACATCTATTACTGTTTGGTAAGGATGGTTTGACA
AAGTTACTCGATGCTTACGACAATGCAGGCGGAAGAACATGGTCAAGAATGGATGAGCATATAATTGAGTTGTTAACAAC
CAGCGCAATAACTGTAGCTGAATTCGCAGAGATATCTGACCTACAAGATATGCGTGAAACAGCTGCTCATATGCTTGCAC
AAAATGTATGA