MEGAResFrom MEG, the Microbial Ecology Group

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ERME

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

  • http://cid.oxfordjournals.org/content/34/4/482.full

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Other Groups in 23S rRNA methyltransferases

Sequences

Download Sequences

>>MEG_2826|Drugs|MLS|23S_rRNA_methyltransferases|ERME
GTGAGCAGTTCGGACGAGCAGCCGCGCCCGCGTCGCCGCAACCAGGATCGGCAGCACCCCAACCAGAACCGGCCGGTGCT
GGGCCGTACCGAGCGGGACCGCAACCGGCGCCAGTTCGGGCAGAACTTCCTCCGCGACCGCAAGACCATCGCGCGCATCG
CCGAGACAGCCGAGCTGCGGCCCGATCTGCCGGTGCTGGAAGCCGGCCCCGTCGAAGGGCTGCTCACCAGGGAACTCGCC
GACCGCGCGCGTCAGGTGACGTCGTACGAGATCGACCCCCGGCTGGCGAAGTCGTTGCGGGAGAAGCTTTCCGGCCACCC
GAACATCGAAGTCGTCAACGCCGACTTCCTCACCGCCGAACCGCCGCCCGAGCCGTTCGCCTTCGTCGGCGCGATCCCCT
ACGGCATCACCTCGGCGATCGTGGACTGGTGCCTGGAGGCGCCGACGATCGAGACGGCGACGATGGTCACGCAGCTGGAG
TTCGCCCGGAAGCGGACCGGCGATTACGGCCGCTGGAGCCGCCTCACGGTGATGACCTGGCCGCTGTTCGAGTGGGAGTT
CGTCGAGAAGGTCGACTCGGCGATCATGCGGCTGCGCAGGCGCGCCGAACCGCTGCTGGAAGGCGCGGCGCTCGAACGCT
ACGAGTCGATGGTCGAGCTGTGCTTCACCGGCGTCGGCGGCAACATCCAGGCGTCGCTTCTGCGCAAGTACCCGAGGCGC
CGCGTCGAGGCGGCGTTCGACCACGCGGGGGTCGGGGGCGGCGCCGTGGTCGCCTACGTCCGGCCGGAGCAGTGGCTCCG
GCTGTTCGAGCGGCTGGATCAGAAGAACGAACCGAGGGGTGGGCAGCCCCAGCGGGGCAGGCGAACCGGCGGACGGGACC
ACGGGGACCGGCGAACCGGCGGGCAGGATCGCGGCGATCGGCGAACCGGCGGCCGCGACCACAGGGACCGGCAAGCCAGC
GGCCACGGCGATCGTCGCAGCAGCGGACGCAATCGCGACGACGGACGAACCGGCGAGCGCGAGCAGGGGGACCAAGGCGG
GCGGCGGGGGCCGTCCGGGGGTGGACGGACCGGCGGACGTCCAGGGCGACGCGGCGGACCCGGGCAGCGGTAG

>>MEG_2827|Drugs|MLS|23S_rRNA_methyltransferases|ERME
GTGAGCAGTTCGGACGAGCAGCCGCGCCCGCGTCGCCGCAACCAGGATCGGCAGCACCCCAACCAGAACCGGCCGGTGCT
GGGCCGTACCGAGCGGGACCGCAACCGGCGCCAGTTCGGGCAGAACTTCCTCCGCGACCGCAAGACCATCGCGCGCATCG
CCGAGACAGCCGAGCTGCGGCCCGATCTGCCGGTGCTGGAAGCCGGCCCCGGCGAAGGGCTGCTCACCAGGGAACTCGCC
GACCGCGCGCGTCAGGTGACGTCGTACGAGATCGACCCCCGGCTGGCGAAGTCGTTGCGGGAGAAGCTTTCCGGCCACCC
GAACATCGAAGTCGTCAACGCCGACTTCCTCACCGCCGAACCGCCGCCCGAGCCGTTCGCCTTCGTCGGCGCGATCCCCT
ACGGCATCACCTCGGCGATCGTGGACTGGTGCCTGGAGGCGCCGACGATCGAGACGGCGACGATGGTCACGCAGCTGGAG
TTCGCCCGGAAGCGGACCGGCGATTACGGCCGCTGGAGCCGCCTCACGGTGATGACCTGGCCGCTGTTCGAGTGGGAGTT
CGTCGAGAAGGTCGACCGCCGGCTGTTCAAGCCGGTGCCCAAGGTCGACTCGGCGATCATGCGGCTGCGCAGGCGCGCCG
AACCGCTGCTGGAAGGCGCGGCGCTCGAACGCTACGAGTCGATGGTCGAGCTGTGCTTCACCGGCGTCGGCGGCAACATC
CAGGCGTCGCTTCTGCGCAAGTACCCGAGGCGCCGCGTCGAGGCGGCGCTCGACCACGCGGGGGTCGGGGGCGGCGCCGT
GGTCGCCTACGTCCGGCCGGAGCAGTGGCTCCGGCTGTTCGAGCGGCTGGATCAGAAGAACGAACCGAGGGGTGGGCAGC
CCCAGCGGGGCAGGCGAACCGGCGGACGGGACCACGGGGACCGGCGAACCGGCGGGCAGGATCGCGGCGATCGGCGAACC
GGCGGCCGCGACCACAGGGACCGGCAAGCCAGCGGCCACGGCGATCGTCGCAGCAGCGGACGCAATCGCGACGACGGACG
AACCGGCGAGCGCGAGCAGGGGGACCAAGGCGGGCGGCGGGGGCCGTCCGGGGGTGGACGGACCGGCGGACGTCCAGGGC
GACGCGGCGGACCCGGGCAGCGGTAG