Fusidic acid inhibits protein synthesis by binding to Elongation Factor G (EF-G), which prevents translocation of the bacterial ribosome. Fusidic acid is most commonly used as a topical antibiotic against infections caused by Staphylococcus species.

References

• http://adc.bmj.com/content/89/1/74.full

Mechanisms

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• Fusidic acid esterases
• Fusidic acid-resistant mutation
• Ribosomal zinc-binding protein

Sequences

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