Cationic antimicrobial peptides
The cationic antimicrobial peptides (CAMPs) span a wide range of natural biosynthetic products that disrupt the bacterial outer membrane, leading to cell death and prevention of bacterial cell proliferation. Few resistance genes are known for the CAMPs.
References
- http://www.sciencedirect.com/science/article/pii/S0005273606000435
Mechanisms
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- Cationic peptide-resistant 16S ribosomal subunit protein
- Defensin-resistant mprF
- Edeine acetyltransferase
- Lipid A modification
- Polymyxin B resistance regulator