MEGAResFrom MEG, the Microbial Ecology Group

Notice: Trying to access array offset on value of type null in /home/meglabuser/megares.meglab.org/vendor/doctrine/annotations/lib/Doctrine/Common/Annotations/DocParser.php on line 967

Aminoglycosides

The aminoglycoside antibiotics are derived from Streptomyces and Micromonospora bacteria. Their method of action is disruption of bacterial protein translation via binding of the 16S rRNA of the 30S subunit of the bacterial ribosome. To reach the ribosome, they must first be actively transported into the cell by transporters on the cell wall. Common drugs in the aminoglycoside class include gentamicin, amikacin, streptomycin, and tobramycin.

References

  • http://onlinelibrary.wiley.com/doi/10.1111/j.1445-5994.2011.02452.x/epdf,http://www.ncbi.nlm.nih.gov/pmc/articles/PMC372903/pdf/microrev00024-0152.pdf

Mechanisms


Notice: Trying to access array offset on value of type null in /home/meglabuser/megares.meglab.org/vendor/doctrine/annotations/lib/Doctrine/Common/Annotations/DocParser.php on line 967

Sequences

Download Sequences