MEGAResFrom MEG, the Microbial Ecology Group

DFRE

The dfr genes in this category of resistance encode a dihydrofolate reductase enzyme that is less vulernable to trimethoprim than wild type.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/6985448

Other Groups in Dihydrofolate reductase

Sequences

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>>MEG_2577|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRE
ATGTTAGCAGCTATTTGGGCCCAAGATGAACAAGGAGTGATTGGTAAAGAAGGCAAATTGCCTTGGCATTTACCCAATGA
CTTGAAATTTTTCAAGGAAAAAACAATTCATAATACATTGGTCTTAGGACGTGCAACTTTCGAAGGCATGGGATGTCGTC
CGCTACCAAATCGAACAACGATTGTCCTAACCAGTAATCCGGATTACCGAGCTGAAGGCGTTTTGGTTATGCATTCCGTA
GAGGAAATTCTTGCGTATGCTGACAACTATGAAGGTGTGACCGTTATTGGTGGAGGTTCTGTCGTTTTTAAAGAACTGAT
TCCCGCATGCGATGTCTTATATCGGACGATGATTCATGAAACGTTTGAAGGCGACACTTTCTTTCCAGAAATCGACTGGT
TTGTTTGGGAAAAAGTTGCCACTGTTCCCGGCGTCGTGGACGAGAAAAATCTCTATGCACATGACTATGAAACGTATCAT
CGAAACGATAAATAA