MEGAResFrom MEG, the Microbial Ecology Group

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DFRC

The dfr genes in this category of resistance encode a dihydrofolate reductase enzyme that is less vulernable to trimethoprim than wild type.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/6985448

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Other Groups in Dihydrofolate reductase

Sequences

Download Sequences

>>MEG_2572|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRC|RequiresSNPConfirmation
ATGACATTATCAATAATTGTCGCTCACGATAAACAAAGAGTCATTGGGTACCAAAATCAATTACCTTGGCACTTACCAAA
TGATTTAAAGCATGTTAAACAACTGACCACTGGGAATACACTTGTAATGGGACGGAAAACTTTTAATTCTATAGGGAAAC
CATTGCCAAATAGACGTAACGTCGTACTCACTAACCAAGCTTCATTTCACCATGAAGGGGTAGATGTTATAAACTCTCTT
GATGAAATTAAAGAGTTATCTGGTCATGTTTTTATATTTGGAGGACAAACGTTATTCGAGGCAATGATTGACCAGGTAGA
TGATATGTATATCACAGTAATAGATGGAAAGTTTCAAGGAGACACATTCTTTCCACCATACACATTCGAAAACTGGGAAG
TCGAATCTTCAGTAGAAGGTCAACTAGATGAAAAAAATACTATACCGCATACATTCTTACATTTAGTGCGTAGAAAAGGG
AAATAG

>>MEG_2573|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRC|RequiresSNPConfirmation
ATGACATTATCAATAATTGTCGCTCACGATAAACAAAGAGTCATTGGGTACCAAAATCAATTACCTTGGCACTTACCAAA
TGATTTAAAGCATATTAAACAACTGACCACTGGGAATACACTTGTAATGGCACGGAAAACTTTTAATTCTATAGGGAAGC
CATTGCCAAATAGACGTAACGTCGTACTCACTAACCAAGCTTCATTTCACCATGAAGGGGTAGATGTTATAAACTCTCTT
GATGAAATTAAAGAGTTATCTGGTCATGTTTTTATATTTGGAGGACAAACGTTATACGAAGCAATGATTGACCAGGTAGA
TGATATGTATATCACAGTAATAGATGGAAAGTTTCAAGGAGACACATTCTTTCCACCATACACATTCGAAAACTGGGAAG
TCGAATCTTCAGTAGAAGGTCAACTAGATGAAAAAAATACTATACCGCATACATTCTTACATTTAGTGCGTAGAAAAGGG
AAATAG