MEGAResFrom MEG, the Microbial Ecology Group

DFRC

The dfr genes in this category of resistance encode a dihydrofolate reductase enzyme that is less vulernable to trimethoprim than wild type.

References

Other Groups in Dihydrofolate reductase

Sequences

Download Sequences

>Tmt|DfrC|Z48233|337-822|486|Trimethoprim|Dihydrofolate_reductase|DFRC|RequiresSNPConfirmation
ATGACATTATCAATAATTGTCGCTCACGATAAACAAAGAGTCATTGGGTACCAAAATCAATTACCTTGGCACTTACCAAA
TGATTTAAAGCATGTTAAACAACTGACCACTGGGAATACACTTGTAATGGGACGGAAAACTTTTAATTCTATAGGGAAAC
CATTGCCAAATAGACGTAACGTCGTACTCACTAACCAAGCTTCATTTCACCATGAAGGGGTAGATGTTATAAACTCTCTT
GATGAAATTAAAGAGTTATCTGGTCATGTTTTTATATTTGGAGGACAAACGTTATTCGAGGCAATGATTGACCAGGTAGA
TGATATGTATATCACAGTAATAGATGGAAAGTTTCAAGGAGACACATTCTTTCCACCATACACATTCGAAAACTGGGAAG
TCGAATCTTCAGTAGAAGGTCAACTAGATGAAAAAAATACTATACCGCATACATTCTTACATTTAGTGCGTAGAAAAGGG
AAATAG

>Tmt|dfrC_1_GU565967|Trimethoprim|Dihydrofolate_reductase|DFRC|RequiresSNPConfirmation
ATGACATTATCAATAATTGTCGCTCACGATAAACAAAGAGTCATTGGGTACCAAAATCAATTACCTTGGCACTTACCAAA
TGATTTAAAGCATATTAAACAACTGACCACTGGGAATACACTTGTAATGGCACGGAAAACTTTTAATTCTATAGGGAAGC
CATTGCCAAATAGACGTAACGTCGTACTCACTAACCAAGCTTCATTTCACCATGAAGGGGTAGATGTTATAAACTCTCTT
GATGAAATTAAAGAGTTATCTGGTCATGTTTTTATATTTGGAGGACAAACGTTATACGAAGCAATGATTGACCAGGTAGA
TGATATGTATATCACAGTAATAGATGGAAAGTTTCAAGGAGACACATTCTTTCCACCATACACATTCGAAAACTGGGAAG
TCGAATCTTCAGTAGAAGGTCAACTAGATGAAAAAAATACTATACCGCATACATTCTTACATTTAGTGCGTAGAAAAGGG
AAATAG

>CARD|phgb|AE015929|1128933-1129419|ARO:3002865|dfrC|Trimethoprim|Dihydrofolate_reductase|DFRC|RequiresSNPConfirmation
CTATTTCCCTTTTCTACGCACTAAATGTAAGAATGTATGCGGTATAGTATTTTTTTCATCTAGTTGACCTTCTACTGAAG
ATTCGACTTCCCAGTTTTCGAATGTGTATGGTGGAAAGAATGTGTCTCCTTGAAACTTTCCATCTATTACTGTGATATAC
ATATCATCTACCTGGTCAATCATTGCCTCGAATAACGTTTGTCCTCCAAATATAAAAACATGACCAGATAACTCTTTAAT
TTCATCAAGAGAGTTTATAACATCTACCCCTTCATGGTGAAATGAAGCTTGGTTAGTGAGTACGACGTTACGTCTATTTG
GCAATGGTTTCCCTATAGAATTAAAAGTTTTCCGTCCCATTACAAGTGTATTCCCAGTGGTCAGTTGTTTAACATGCTTT
AAATCATTTGGTAAGTGCCAAGGTAATTGATTTTGGTACCCAATGACTCTTTGTTTATCGTGAGCGACAATTATTGATAA
TGTCATG