DFRB
The dfr genes in this category of resistance encode a dihydrofolate reductase enzyme that is less vulernable to trimethoprim than wild type.
References
- http://www.ncbi.nlm.nih.gov/pubmed/6985448
Other Groups in Dihydrofolate reductase
Sequences
>>MEG_2557|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
atgaatgaaggaaaaaatgaggtcagtacttcagctgctggccggttcgcattcccatcaaacgccacgtttgccttggg
ggatcgcgtacgcaagaagtctggcgctgcttggcaggggcgcattgtcgggtggtactgcacaacacttacccctgaag
gctacgccgtcgagtccgaatctcacccagactcagtccagatttatcccatgactgcgcttgaacgggtggcctga
>>MEG_2558|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
atggaacgaagtagcaatgaagtcagtaatccagttgctggcaattttgtattcccatcgaacgccacgtttggtatagg
agatcgcgtgcgcaagaaatccggcgccgcctggcaaggtcagattgtcggctggtactgcacaaatttgacccccgaag
gctacgccgtcgagtctgaggctcacccaggctcagtacagatttatcctgttgcggcgcttgagcgcatcaactga
>>MEG_2559|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
atgaatcaaagtagcaattgcatcagcactccagttgttggacagtttgcgctgccatttcaacccacgttcggcctggg
agatcgcgtacgcaagaagtctggcgccgcttggcaaggtaaagttgtcggctggtactgcacaaaattaacccctgaag
gctacgcggtcgagtccgaagctcatccaggctcagtgcagatttatcctgtggctgcgcttgaacgcgtggcctaa
>>MEG_2560|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
atgaatgaaggaaaaaatgaggtcagtacttcagctgctggccggttcgcattcccatcaaacgccacgtttgcctgggg
ggatcgcgtacgcaagaagtctggcgctgcttggcaggggcgcattgtcgggtggtactgcacaacacttacccctgaag
gctacgccgtcgagtccgaatctcacccaggctcagtccagatttatcccatgactgcgcttgaacgggtggcctga
>>MEG_2561|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
atggaacgaagtagcaatgaagtcagtaatccagttgctggcaattttgtattcccatcgaacgccacgtttggtatggg
agatcgcgtgcgcaagaaatccggcgccgcctggcaaggtcagattgtcgggtggtactgcacaaatttgacccccgaag
gctacgccgtcgagtctgaggctcacccaggctcagtacagatttatcctgttgcggcgcttgaacgcatcaactga
>>MEG_2562|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
atgggtcaaagtagccatgaagccaacgctcccgttgcagggcagtttgcacttcccctgagtgccacctttggcttcgg
agatcgcgtacgcaagaaatctggtgccgcttggcagggtcaagtcgtcggttggtattgcacaaaactcactcctgaag
gctatgcggtcgagtccgaatcccacccaggctcagtgcaaatttatcctgtggctgcacttgaacgtgtggcctaa
>>MEG_2563|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGACCAAGGCAGAAGTGAAGTCAGTAATCCAGTTGCTGGCCAGTTTGCGTTCCCTTCAAACGCCGCGTTCGGAATGGG
AGATCGCGTGCGCAAGAAATCTGGCGCCGCTTGGCAAGGCCAGATTGTCGGGTGGTACTGCACAAAATTGACCCCTGAAG
GGTACGCTGTCGAGTCTGAGGCTCACCCTGGCTCGGTACAGATTTATCCTGTTGCGGCACTGGAACGCATCAACTGA
>>MEG_2564|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGCAGCGTGTCGTCGGGCCACATAGAACACCTAGAAGTTCACAAGAAAGGTCGGAAATGGAACGAAGTAGCAATGAAGT
CAGTAATCCAGTTGCTGGCAATTTTGTATTCCCATCGAACGCCACGTTTGGTATGGGAGATCGCGTGCGCAAGAAATCCG
GCGCCGCCTGGCAAGGTCAGATTGTCGGGTGGTACTGCACAAATTTGACCCCCGAAGGCTACGCCGTCGAGTCTGAGGCT
CACCCAGGCTCAGTACAGATTTATCCTGTTGCGGCGCTTGAACGCATCAACTGA
>>MEG_2565|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGGTCAAAGTAGCGATGAAGCCAACGCTCCCGTTGCAGGGCAGTTTGCGCTTCCCCTGAGTGCCACCTTTGGCTTAGG
GGATCGCGTACGCAAGAAATCTGGTGCCGCTTGGCAGGGTCAAGTCGTCGGTTGGTATTGCACAAAACTCACTCCTGAAG
GCTATGCGGTCGAGTCCGAATCCCACCCAGGCTCAGTGCAAATTTATCCTGTGGCTGCACTTGAACGTGTGGCCTAA
>>MEG_2566|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGACCAACACAACAATGGAGTCAGTACTCTAGTTGCTGGCCAGTTTGCGCTCCCATCGCACGCCACGTTTGGCCTGGG
AGATCGCGTGCGCAAGAAATCTGGCGCCGCTTGGCAGGGTCAAGTTGTCGGGTGGTACTGCACAAAACTGACCCCTGAAG
GCTATGCCGTCGAGTCCGAGTCTCACCCCGGTTCAGTACAGATTTATCCTGTGGCTGCGCTTGAACGCGTGGCCTGA
>>MEG_2567|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGACCAAGGTAGCAATGAAGTCATTAATCCAGTCGCTGGCCAGTTTGCGTCCCCATCGAACGCCACGTTTGGTATGGG
AGATCGCGTGCGCAAGAAATCTGGCGCCGCCTGGCAAGGTCAGATTGTCGGGTGGTACAGCACAAAGTTGACCCCTGAAG
GCTACGCTGTCGAGTCTGAGGCTCACCCTGGCTCGGTGCAGATTTATCCTGTTGCCGCGCTTGAACGCGTCAACTGA
>>MEG_2568|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGACCAAGGTAGCAATGAAGTCGGTAATCCAGTTGCGGGCCAGTTTTCGTTCCCATCGAACGCCGCGTTTAGTATGGG
AGATCGCGTGCGCAAGAAATCGGGCGCCGCTTGGCAAGGTCAGATTGTCGGGTGGTACTGCACAAAGTTGACCCCTGAAG
GCTACGCTGTCGAGTCTGAGGCTCACCCTGGCTCGGTACAGATTTATCCTGTTGCGGCGCTTGAACGCATCAACGGAGTT
CAAGGTTGA
>>MEG_2569|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGAATGAAGGAAAAAATGAGGTCAGTACTTCAGCTGCTGGCCGGTTCGCATTCCCATCAAACGCCACGTTTGCCTTGGG
GGATCGCGTACGCAAGAAGTCTGGCGCTGCTTGGCAGGGGCGCATTGTCGGGTGGTACTGCACAACACTTACCCCTGAAG
GCTACGCCGTCGAGTCCGAATCTCACCCAGGCTCAGTCCAGATTTATCCCATGACTGCGCTTGAACGGGTGGCCTGA
>>MEG_2570|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGACCAACACAACAATGGAGTCAGTACTCTAGTTGCTGGCCAGTTTGCGCTCCCATCGCACGCCACGTTTGGCCTGGG
AGATCGCGTGCGCAAGAAATCTGGCGCCGCTTGGCAGGGTCAAGTTGTCGGGTGGTACTGCACAAAACTGACCCCTGAAG
GCTATGCCGTCGAGTCCGAGTCTCACCCCGGTTCAGTACAGATTTACCCTGTGGCTGCGCTTGAACGCGTGGCCTGA
>>MEG_2571|Drugs|Trimethoprim|Dihydrofolate_reductase|DFRB
ATGGATCAAAGTAGTAAGGAAGTCAGTTCTCCAGCTACTGACCAGTTTGCGCTCCCATTCCGCGCCACGTTTGGCCTGGG
AGATCGCGTACGCAAGAAATCTGGCGCCGCTTGGCAGGGTCAAGTTGTCGGCTGGTACAGCACAAAACTAACCCCAGAAG
GCTATGCCGTCGAGTCCGAGTCTCATCCGGGCTCTGTACAAATCTATCCTGTTGCCGCGCTTGAACGCGTGGCCTAA