MEGAResFrom MEG, the Microbial Ecology Group

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Tetracycline resistance ribosomal protection proteins

Similar to the elongation factors, the ribosomal protection proteins utilize GTP to free tetracycline from its bound state on the ribosome, thus reversing the inhibitory effect of the tetracycline antibiotics. The most commonly studied ribosomal protection proteins are tetO and tetM.

References

  • http://aac.asm.org/content/47/12/3675

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Other Mechanisms in Tetracyclines

Groups

Sequences

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