MEGAResFrom MEG, the Microbial Ecology Group

TETX

Resistance to tetracyclines can be mediated by direct inactivation of the tetracycline molecule via hydroxylation or other mechanisms. The tetX, tet37 and tet34 have been characterized as acting as tetracycline inactivators.

References

Other Groups in Tetracycline inactivation enzymes

Sequences

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>Tet|tetX_1_GU014535|Tetracyclines|Tetracycline_inactivation_enzymes|TETX
ATGACAATGCGAATAAATACAGACAAACAAATGAATTTACTTAGTGATAAGAACGTTGCAATAATTGGTGGTGGACCCGT
TGGACTGACTATGGCAAAATTATTACAGCAAAACGGCATAGACGTTTCAGTTTACGAAAGAGACAACGACCGAGAGGCAA
GAATTTTTGGTGGAACCCTTGACCTACACAAAGGTTCAGGTCAGGAAGCAATGAAAAAAGCGGGATTGTTACAAACTTAT
TATGACTTAGCCTTACCAATGGGTGTAAATATTGCTGATGAAAAAGGCAATATTTTATCCACAAAAAATGTAAAGCCCGA
AAATCGATTTGACAATCCTGAAATAAACAGAAATGACTTAAGGGCTATCTTGTTGAATAGTTTAGAAAACGACACGGTTA
TTTGGGATAGAAAACTTGTTATGCTTGAACCTGGTAAGAAGAAGTGGACACTAACTTTTGAGAATAAACCGAGTGAAACA
GCAGATTTGGTTATTCTTGCCAATGGCGGGATGTCCAAGGTAAGAAAATTTGTTACCGACACGGAAGTTGAAGAAACAGG
TACTTTCAATATACAAGCCGATATTCATCAACCAGAGATAAACTGTCCTGGATTTTTTCAGCTATGCAATGGAAACCGGC
TAATGGCATCTCACCAAGGTAATTTATTATTTGCTAACCCCAATAATAATGGTGCATTGCATTTTGGAATAAGTTTTAAA
ACACCTGATGAATGGAAAAACCAAACGCAGGTAGATTTTCAAAACAGAAATAGTGTCGTTGATTTTCTTCTGAAAAAATT
TTCCGATTGGGACGAACGCTACAAAGAATTGATTCATGCGACGTTGTCATTTGTAGGATTGGCTACACGGATATTTCCTT
TAGAAAAGCCTTGGAAAAGCAAGCGCCCATTACCCATAACAATGATTGGGGATGCCGCACATTTGATGCCGCCTTTTGCA
GGGCAGGGAGTAAATAGTGGGTTGGTGGATGCCTTGATATTGTCTGATAATCTAGCCGATGGAAAATTTAATAGCATTGA
AGAGGCTGTTAAAAATTATGAACAGCAAATGTTTATCTATGGCAAAGAAGCACAAGAAGAATCAACTCAAAACGAAATTG
AAATGTTTAAACCCGACTTTACGTTTCAGCAATTGTTAAATGTATAA

>Tet|tetX_3_AB097942|Tetracyclines|Tetracycline_inactivation_enzymes|TETX
ATGACTTTACTAAAATATAAAAAAATTACAATAATTGGTGCCGGGCCTGTTGGATTAACAATGGCGAGATTGTTACAGCA
AAACGGCGTGGACATTACAGTTTACGAGAGAGACAAAGACCAAGATGCAAGGATTTTTGGTGGGACACTTGATCTGCACA
GGGATTCGGGACAGGAAGCAATGAAAAGAGCGGGATTGTTACAAACTTATTATGACTTAGCTTTACCAATGGGTGTAAAT
ATTGTTGATGAAAAGGGCAATATTTTAACCACAAAAAATGTAAGGCCCGAAAATCGTTTTGACAATCCTGAAATAAACAG
AAATGACTTAAGGACTATCCTATTAAATAGTTTACAAAATGATACCGTCATTTGGGATAGAAAACTTGTTACCCTTGAAC
CTGATAAGGAGAAGTGGATACTAACTTTTGGGGATAAATCGAGTGAAACAGCAGATCTGGTTATTATTGCCAATGGTGGA
ATGTCTAAAGTAAGAAAATTTGTTACCGACACGGAAGTTGAAGAAACAGGTACTTTCAATATACAAGCCGATATTCATCA
ACCAGAGGTGAACTGTCCTGGATTTTTTCAGCTATGCAATGGAAACCGGCTAATGGCTGCTCATCAAGGTAATTTATTAT
TTGCGAATCCTAATAATAATGGTGCATTGCATTTTGGAATAAGTTTTAAAACACCTGATGAATGGAAAAGCAAAACGCAG
GTAGATTTTCAAGACAGAAATAGTGTCGTTGATTTTCTCCTGAAAAAATTTTCCGATTGGGACGAACGCTACAAAGAACT
GATTCGTTTGACATCATCTTTTGTAGGGTTAGCGACACGAATATTTCCCTTAGATAAGTCTTGGAAAAGTAAGCGTCCAT
TACCCATAACGATGATTGGAGATGCTGCTCATTTGATGCCTCCTTTTGCAGGACAAGGCGTAAACAGCGGGTTGATGGAT
GCCTTGATATTGTCGGATAATCTGACCAATGGGAAATTTAACAGCATTGAAGAGGCTATTGAAAATTATGAACAGCAAAT
GTTTGCTTATGGAAGAGAAGCACAGACAGAATCAATAATAAACGAAACGGAAATGTTCAGCCTCGACTTTTCGTTCCAAA
AACTAATGAATCTATAA

>Tet|TetX|M37699|586-1752|1167|Tetracyclines|Tetracycline_inactivation_enzymes|TETX
ATGACAATGCGAATAGATACAGACAAACAAATGAATTTACTTAGTGATAAGAACGTTGCAATAATTGGTGGTGGACCCGT
TGGACTGACTATGGCAAAATTATTACAGCAAAACGGCATAGACGTTTCAGTTTACGAAAGAGACAACGACCGAGAGGCAA
GAATTTTTGGTGGAACCCTTGACCTACACAAAGGTTCAGGTCAGGAAGCAATGAAAAAAGCGGGATTGTTACAAACTTAT
TATGACTTAGCCTTACCAATGGGTGTAAATATTGCTGATAAAAAAGGCAATATTTTATCCACAAAAAATGTAAAGCCCGA
AAATCGATTTGACAATCCTGAAATAAACAGAAATGACTTAAGGGCTATCTTGTTGAATAGTTTAGAAAACGACACGGTTA
TTTGGGATAGAAAACTTGTTATGCTTGAACCTGGTAAGAAGAAGTGGACACTAACTTTTGAGAATAAACCGAGTGAAACA
GCAGATTTGGTTATTCTTGCCAATGGCGGGATGTCCAAGGTAAGAAAATTTGTTACCGACACGGAAGTTGAAGAAACAGG
TACTTTCAATATACAAGCCGATATTCATCAACCAGAGATAAACTGTCCTGGATTTTTTCAGCTATGCAATGGAAACCGGC
TAATGGCATCTCACCAAGGTAATTTATTATTTGCTAACCCCAATAATAATGGTGCATTGCATTTTGGAATAAGTTTTAAA
ACACCTGATGAATGGAAAAACCAAACGCAGGTAGATTTTCAAAACAGAAATAGTGTCGTTGATTTTCTTCTGAAAGAATT
TTCCGATTGGGACGAACGCTACAAAGAATTGATTCATACGACGTTGTCATTTGTAGGATTGGCTACACGGATATTTCCTT
TAGAAAAGCCTTGGAAAAGCAAGCGCCCATTACCCATAACAATGATTGGGGATGCCGCACATTTGATGCCGCCTTTTGCA
GGGCAGGGAGTAAATAGTGGGTTGGTGGATGCCTTGATATTGTCTGATAATCTAGCCGATGGAAAATTTAATAGCATTGA
AGAGGCTGTTAAAAATTATGAACAGCAAATGTTTATGTATGGCAAAGAAGCACAAGAAGAATCAACTCAAAACGAAATTG
AAATGTTTAAACCCGACTTTACGTTTCAGCAATTGTTAAATGTATAA