MEGAResFrom MEG, the Microbial Ecology Group

Pleuromutilin

Pleuromutilins are natural fungal products that target bacterial protein translation by binding the the 23S rRNA, blocking the ribosome P site at the 50S subunit. They are mostly used for agriculture and veterinary purposes.

References

  • https://www.ncbi.nlm.nih.gov/pubmed/20112168,https://www.ncbi.nlm.nih.gov/pubmed/931799,https://www.ncbi.nlm.nih.gov/pubmed/16569865,https://www.ncbi.nlm.nih.gov/pubmed/15554968,https://www.ncbi.nlm.nih.gov/pubmed/17360517,https://www.ncbi.nlm.nih.gov/pubmed/11555289

Mechanisms

Sequences

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