MEGAResFrom MEG, the Microbial Ecology Group

Oxazolidinone

Oxazolidinones are a class of synthetic antibiotics discovered the the 1980's. They inhibit protein synthesis by binding to domain V of the 23S rRNA of the 50S subunit of bacterial ribosomes. Linezolid is the only member of this class currently in clinical use.

References

  • https://www.ncbi.nlm.nih.gov/pubmed/18757750

Mechanisms

Sequences

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