MEGAResFrom MEG, the Microbial Ecology Group

INIC

The ini pump-related genes are necessary for sensitivity to ethambutol, therefore resistance to ethambutol can occur when these proteins develop specific mutations that prevent drug accumulation in the bacterial cell.

References

Sequences

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>CARD|pvgb|AL123456|412756-414238|ARO:3003451|Mycobacterium|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_iniC|INIC|RequiresSNPConfirmation
GTGAGCACCAGCGACCGGGTCCGCGCGATTCTGCACGCAACCATCCAGGCCTACCGGGGTGCGCCGGCCTATCGTCAGCG
TGGCGACGTTTTTTGCCAGCTGGACCGCATCGGTGCGCGCCTAGCCGAACCGCTGCGCATCGCGTTGGCTGGCACACTCA
AGGCCGGAAAATCCACTCTCGTCAACGCCCTTGTCGGCGACGACATCGCTCCGACCGATGCCACCGAGGCCACCCGGATT
GTGACCTGGTTCCGGCACGGTCCGACACCGCGGGTCACCGCCAACCATCGCGGCGGTCGACGCGCCAACGTGCCGATCAC
CCGTCGGGGCGGGCTGAGTTTCGACCTGCGCAGGATCAACCCGGCCGAGCTGATCGACCTGGAAGTCGAGTGGCCAGCCG
AGGAACTCATCGACGCCACCATTGTTGACACCCCGGGAACGTCGTCGTTGGCATGCGATGCCTCCGAGCGCACGTTGCGG
CTGCTGGTCCCCGCCGACGGGGTGCCTCGGGTGGATGCGGTGGTGTTCCTGTTGCGCACCCTGAACGCCGCTGACGTCGC
GCTGCTCAAACAGATCGGTGGGCTGGTCGGCGGGTCGGTGGGAGCCCTGGGCATCATCGGGGTGGCGTCTCGCGCGGATG
AGATCGGCGCGGGCCGCATCGACGCGATGCTCTCGGCCAACGACGTGGCCAAGCGGTTCACCCGCGAACTGAACCAGATG
GGCATTTGCCAGGCGGTGGTGCCGGTATCCGGACTTCTTGCGCTGACCGCGCGCACACTGCGCCAGACCGAGTTCATCGC
GCTGCGCAAGCTGGCCGGTGCCGAGCGCACCGAGCTCAATAGGGCCCTGCTGAGCGTGGACCGTTTTGTGCGCCGGGACA
GTCCGCTACCGGTGGACGCGGGCATCCGTGCGCAATTGCTCGAGCGGTTCGGCATGTTCGGCATCCGGATGTCGATTGCC
GTGCTGGCGGCCGGCGTGACCGATTCGACCGGGCTGGCCGCCGAACTGCTGGAGCGCAGCGGGCTGGTGGCGCTGCGCAA
TGTGATAGACCAGCAGTTCGCGCAGCGCTCCGACATGCTTAAGGCGCATACCGCCTTGGTCTCCTTGCGCCGATTCGTGC
AGACGCATCCGGTGCCGGCGACCCCGTACGTCATTGCCGACATCGACCCGTTGCTAGCCGACACCCACGCCTTCGAAGAA
CTCCGAATGCTAAGCCTTTTGCCTTCGCGGGCAACGACATTGAACGACGACGAAATCGCGTCGCTGCGCCGCATCATCGG
CGGGTCGGGCACCAGTGCCGCCGCTCGGCTGGGCCTGGATCCCGCGAATTCTCGCGAGGCCCCGCGCGCCGCGCTGGCCG
CAGCGCAACACTGGCGTCGCCGTGCGGCGCATCCACTCAACGATCCGTTCACTACCAGGGCCTGTCGCGCGGCGGTGCGC
AGCGCCGAGGCGATGGTGGCGGAGTTCTCTGCTCGCCGCTGAC