MEGAResFrom MEG, the Microbial Ecology Group

NIME

The nim genes encode inducible nitroimidazole reductases, which modify metronidazole and cause resistance.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549250/

Other Groups in nim nitroimidazole reductase

Sequences

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>>MEG_4183|Drugs|Metronidazole|nim_nitroimidazole_reductase|NIME
atgttcagagaaatgcgtcgtaaacgacagttgttgccacaagaagagagcgtggcaattcttgaaaaaatgacaaacgg
gactttagctctccacggagataatggctatccttatgccgttcctctcagttatttttatgctgatggcaaaatctatt
ttcattgcgccaagatagggcataaggtggacgctattatgcaaaacaataaagtatcgttttgcgttgtggaacaagac
aatattaaacctgccgaattcacgacctactttcgaagtgtgatagtctttggaaaggcctatattttaaccgacgaaac
agaaaaacgtatggctatgactttgctggtgaataaatattctttcggtgagccaggtttgtctgatgaaatagccaaaa
gcatcaaccatctactgatggtaaagatcgatatcgaacacatgacgggcaaggaggccatcgatttggttagagagaaa
gaaaagttttgtacttcagagaaaacctcttga

>>MEG_4184|Drugs|Metronidazole|nim_nitroimidazole_reductase|NIME
ATGTTCAGAGAAATGCGTCGTAAACGACAGTTGTTGCCACAAGAAGAGAGCGTGGCAATTCTTGAAAAAATGACAAACGG
GACTTTAGCTCTCCACGGAGATAATGGCTATCCTTATGCCGTTCCTCTCAGTTATTTTTATGCTGATGGCAAAATCTATT
TTCATTGCGCCAAGATAGGGCATAAGGTGGACGCTATTATGCAAAACAATAAAGTATCGTTTTGCGTTGTGGAACAAGAC
AATATTAAACCTGCCGAATTCACGACCTACTTTCGAAGTGTGATAGTCTTTGGAAAGGCCTATATTTTAACCGACGAAAC
AGAAAAACGTATGGCTATGACTTTGCTGGTGAATAAATATTCTTTCGGTGAGCCAGGTTTGTCTGATGAAATAGCCAAAA
GCATCAACCATCTACTGATGGTAAAGATCGATATC

>>MEG_4185|Drugs|Metronidazole|nim_nitroimidazole_reductase|NIME
ATGTTCAGAGAAATGCGGCGTAAGCGACAGTTGTTGCCACAAGAAGAGAGCGTGGCAATTCTTGAAAAAATGACAAACGG
GACTTTAGCTCTCCACGGAGATAATGGCTATCCTTATGCCGTTCCTCTCAGTTATGTTTATGCTGATGGCAAAATCTATT
TTCATTGCGCCAAGATAGGGCATAAGGTGGACGCTATTATGCAAAACAATAAAGTATCGTTTTGCGTTGTGGAACAAGAC
AATATTAAACCTGCCGAATTCACGACCTACTTTCGAAGTGTGATAGTCTTTGGAAAGGCCTATATTTTAACCGACGAAAC
AGAAAAACGTATGGCTTTGACTTTGCTGATGAATAAATATTCTTTCGGTGAGCCAGGTTTGTCTGATGAAATAGCCAAAA
GCTTCAACCATCTACTGATGGTAAAGATCGATATCGAGCACATGACAGGCAAGGAAGC