MEGAResFrom MEG, the Microbial Ecology Group

VGBB

The vgb genes encode lyases that catalyze an elimination reaction across the streptogramin B ester bond. This inactivates the antibiotic molecule.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/11467949

Other Groups in Streptogramin B ester bond cleavage

Sequences

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>>MEG_7693|Drugs|MLS|Streptogramin_B_ester_bond_cleavage|VGBB
ATGAATTTTTATTTAGAGGAGTTTAACTTGTCTATTCCCGATTCAGGTCCATACGGTATAACTTCATCAGAAGACGGAAA
GGTATGGTTCACACAACATAAGGCAAACAAAATCAGCAGTCTAGATCAGAGTGGTAGGATAAAAGAATTCGAAGTTCCTA
CCCCTGATGCTAAAGTGATGTGTTTAATTGTATCTTCACTTGGAGACATATGGTTTACAGAGAATGGTGCAAATAAAATC
GGAAAGCTCTCAAAAAAAGGTGGCTTTACAGAATATCCATTGCCACAGCCGGATTCTGGTCCTTACGGAATAACGGAAGG
TCTAAATGGCGATATATGGTTTACCCAATTGAATGGAGATCGTATAGGAAAGTTGACAGCTGATGGGACTATTTATGAAT
ATGATTTGCCAAATAAGGGATCTTATCCTGCTTTTATTACTTTAGGTTCGGATAACGCACTTTGGTTCACGGAGAACCAA
AATAATTCTATTGGAAGGATTACAAATACAGGGAAATTAGAAGAATATCCTCTACCAACAAATGCAGCGGCTCCAGTGGG
TATCACTAGTGGTAACGATGGTGCACTCTGGTTTGTCGAAATTATGGGCAACAAAATAGGTCGAATCACTACAACTGGTG
AGATTAGCGAATATGATATTCCAACTCCAAACGCACGTCCACACGCTATAACCGCGGGGAAAAATAGCGAAATATGGTTT
ACTGAATGGGGGGCAAATCAAATCGGCAGAATTACAAACGACAAAACAATTCAAGAATATCAACTTCAAACAGAAAATGC
GGAACCTCATGGTATTACCTTTGGAAAAGATGGATCCGTATGGTTTGCATTAAAATGTAAAATTGGGAAGCTGAATTTGA
ACGAATGA