MEGAResFrom MEG, the Microbial Ecology Group

MPHB

The mph genes encode macrolide phosphotransferases that have been shown to confer resistance to erythromycin by inactivation of the antibiotic molecule via phosphorylation.

References

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC94651/

Other Groups in Macrolide phosphotransferases

Sequences

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>>MEG_4031|Drugs|MLS|Macrolide_phosphotransferases|MPHB
atgagtaaagatattaaacaagtaatcgagatagcaaaaaaacacaatctttttctaaaagaagaaacgatacagtttaa
tgaatcagggcttgattttcaagctgtttttgcacaagataataatggaattgattgggttctaagattgcctagacggg
aagatgtgatgcctagaacaaaggtagaaaaacaagctttggatttggtaaataagtacgctatatcctttcaggcacca
aactggatcatttacacagaggaactaatagcttataaaaagttagatggtgtgccagcaggtacgatagatcataacat
aggtaactatatttgggagatagacataaataatgttccagaattatttcacaagtcgctaggcagggtgttagcagagc
ttcatagcatacctagtaataaagccgcagcgcttgatcttgtagtacacacaccagaagaagcaagaatgtcaatgaag
cagcgtatggatgcagtaagagcaaagttcggagtaggtgagaatctatggaacagatggcaagcgtggttgaatgatga
tgatatgtggcctaagaaaactggactgattcatggagatgtacatgccggacatactatgattgataaggatgccaatg
tgactggattaatcgattggactgaagcgaaggttacagatgtttcgcatgactttattttcaactatagagcttttggg
gaagaagggttagaagctttaattctcgcttataaggaaattggtggatattactggcctaaaatgaaagagcatattat
cgaacttaatgcagcatacccagtttcaatcgctgagtttgcattagtgtctggaattgaggaatatgagcagatggcaa
aggaagcattggaagtacaaggttcgtaa

>>MEG_4032|Drugs|MLS|Macrolide_phosphotransferases|MPHB
ttgaacaaacagaaagcggtagaaatagcaagaaagtatggtttggaagttaaagatgagtccatcatattcaacgagtc
cggtttagattttctggttgcttatgcagaagacgataaaggcgaagaatgggtgctaaggtttccgagacgggacgatg
tgatgccaaggacgatagtggagaagaaagcactggatcttgtaaataaatatgccacttttcaggttccagtctggtcg
gtttatgaaggcgatctaatagcttataaaaagttaatcggagtgccagcaggcacgattgatccggagattcaaaacta
tgtgtgggagatggattatgaaaatgtgcctgaacaatttcaccagacattagccaaagcgttggcttcgctacacacag
ttccgaaaacagaggctcttaaagtaggcctgtttgtccagacagcagaagaggcaagaaaatcgatgattgagcgtatg
aaaaaggttaaagcgaagtttggcgtaggcgaatccttatggaaccgctggcaggcctgggtaaaaaatgaggaattgtg
gcctcagagaacaggtctgattcatggggatgttcatgctggccacacgatgattgataaagatgctaacttaacaggtt
ttatcgactggaccgaagcaaaagtaacggatgtatcaaatgactttgttttccagtaccgggtattcggggaggcagcc
ctggagaaactgatcaactattaccggcaagcaggtgggatttactggcctgccatgaaagagcacgtcattgaacttaa
tgcggcataccctgttgcgatagctgagtttgcgattatctcaggcttggaagaatatgagcagatggcgaaagaaacat
tggaagtgaatgaccgctag

>>MEG_4033|Drugs|MLS|Macrolide_phosphotransferases|MPHB
ATGCCGACGATCCACGTCTCAATAGTATCGTTCAGCAACTCTTTCGCGTACTCCGGGGGTTACATGACTGAAGAGTGCGG
GGAAATTGTTTTCTGGACGCTGCGAAAAAAGTTTGTCGCCAGTAGCGACGAGATGCCGGAACACAGCTCCCAGGTAATGT
ATTACTCGCTGGCTATCGGTCATCACGTTGGCGTGATTGATTGTCTGAATGTCACCTTCCGCTGCCCACTGACGGAATAC
GAAGATTGGCTTGCACTGGTCGAAGAGGAGCAAGCCCGACGTAAGATGCTGGGGGTGATGACTTTTGGTGAGATTGTTAT
TGACGCCAGCCACACCGCCCTGTTGACCCGGGCATTCGCGCCACTGGCAGATGACGCGACGTCTGTGTGGCAAGCGCGTA
GCATTCAATTCATTCATCTGTTGGATGAAATTGTGCTGGAACCGGCTATCTATCTGATGGCCAGAAAAATTGCGTGA