MEGAResFrom MEG, the Microbial Ecology Group

MPHB

The mph genes encode macrolide phosphotransferases that have been shown to confer resistance to erythromycin by inactivation of the antibiotic molecule via phosphorylation.

References

Other Groups in Macrolide phosphotransferases

Sequences

Download Sequences

>CARD|phgb|AHFH01000028|508530-509427|ARO:3003072|Bacillus|MLS|Macrolide_phosphotransferases|MPHB
ATGAATACACTTAAAGTGAAACAATTAGCAAATAAGGAAGGACTAAATATATTAGAAGATTCAATAGAAATCAATGAATC
TGGCGTTGACTTTCAAGTAGCACACGTCAAAGAACAAAACGGGGATAAATGGATACTACGAATTCCTCGTAGACGAGAAT
CTATGAGACATGCTCTACGTGAAAAAGAAGCATTAGAAATCATGAAAAAACATGCAGAATTCCAAGTTCCTGATTGGTCT
ATATTTTCTGAGGAACTAATTGCTTATAAACAACTAAGTGGCGTTCCTGCCGCTACTATCGATATAGAACAACAAGGTTA
TATATGGACCTTTAACGAAAAGGATGTACCAACTGAATACTATATTTCCTTAGGAAAAGTTTTAGCGAATTTACACTCAT
TACCTCAGCAAAAATTTAATAGTATAGGTGTTGAAATTCTTACTGCTAATGAATTAAGAACTTCTATGAAACAAAGGATG
AATCGAGTGAAGGAACAATACCACATCAATCAAAACTTATGGGATCGTTGGCAAGCATGGCTAGCTGAAGACTCTTTTTG
GCCATCTCACGTAGGAGTAAAGCATGGGGATATCCATCCAGGTCATATCCTGATTGATAATAAAAATAAGGTAACTGGCT
TAATCGATTGGACAGAAGTAGGGATAGGTGATGTATCTATAGATTTCACATCGCATTATCTACTCTTTGGAAAGGATGGA
CTAACAAAGTTAATTCACTCTTATGATAACGCTGGCGGTAAAACTTGGTCAAGAATGGATGAACATATTATCGAACTTCT
AACAACGAGTAGTATTACTGTTGCTGAATACGCTCAAGTGTCAGGTTTGAAAGACATGCATGAAATAGCTGTACACATGC
TATCAACTGAAAGTTAAT

>CARD|phgb|AHFH01000066|19120-20020|ARO:3000318|mphB|MLS|Macrolide_phosphotransferases|MPHB
CTAGCGGTCATTCACTTGCAATGTTTCTTTCGCCATCTGCTCATATTCTTCCAAACCTGAGATAATCGCAAACTCAGCTA
TCGCAACAGGGTATGCAGCATTAAGTTCAATGACGTGCTCTTTCATGGCAGGCCAGTAAATTCCGCCTGCTTGCCGGTAA
TGTTGGATCAGTTTCTCCAGGGATGCTTCCCCAAATGCCCGGTACTGGAAAACAAAGTCATTTGATACATCCGTTACTTT
TGCTTCAGTCCAGTCGATTAAACCGGTTACGTTAGCATCTTTATCAATCATCGTGTGGCCAGCATGAACATCACCGTGAA
TCAGGCCTGTTTTCTGCGGCCACAATTCTTCATTTTTTATCCAGGCCTGCCAGCGGTTCCATAAGGATTTTCCTACATCA
AACTTCGCCTTAACCTTTTCCATACGCTCAATCATCGATTTTCTGGCCTCTTCTGCTGTCTGGACAAAAAGGCCTACTTT
AAGAGCCTCTTCTTTCGGAATTGTGTGTAGCGAAGCCAACGCTTTGGCTAATGTCTGGTGAAATCGTTCAGGTACATTTT
CATAATCCATCTCCCACAAATAATTTTGAATCTCTGGATCAATTGTGCCTGCTGGCACTCCGGTTAACTTTTTATAAGCT
ATTAGATCGTTTTTATAAAGCGACCAGACTGGAACCTGAAAAGTGGCATATTTGTTTACAAGATCCAGTGCTTTCTTCTC
CACTATAGTCCTAGGCATCACATCGTCTCGTCTCGGAAACCTTAGCACCCATTCTTCGCCTTTATAATCTTCTGCATACG
CAACTAGAAAATCTAAACCGGACTCGTTGAATATAATGGATCCCTCTTTAACTTCCAAGCCATACTTTCTTGCTATTTCT
ATCGCTTTTTGTTTGTTCAAA

>424|D85892.1|D85892|MLS|Macrolide_phosphotransferases|MPHB
ATGAGTAAAGATATTAAACAAGTAATCGAGATAGCAAAAAAACACAATCTTTTTCTAAAAGAAGAAACGATACAGTTTAA
TGAATCAGGGCTTGATTTTCAAGCTGTTTTTGCACAAGATAATAATGGAATTGATTGGGTTCTAAGATTGCCTAGACGGG
AAGATGTGATGCCTAGAACAAAGGTAGAAAAACAAGCTTTGGATTTGGTAAATAAGTACGCTATATCCTTTCAGGCACCA
AACTGGATCATTTACACAGAGGAACTAATAGCTTATAAAAAGTTAGATGGTGTGCCAGCAGGTACGATAGATCATAACAT
AGGTAACTATATTTGGGAGATAGACATAAATAATGTTCCAGAATTATTTCACAAGTCGCTAGGCAGGGTGTTAGCAGAGC
TTCATAGCATACCTAGTAATAAAGCCGCAGCGCTTGATCTTGTAGTACACACACCAGAAGAAGCAAGAATGTCAATGAAG
CAGCGTATGGATGCAGTAAGAGCAAAGTTCGGAGTAGGTGAGAATCTATGGAACAGATGGCAAGCGTGGTTGAATGATGA
TGATATGTGGCCTAAGAAAACTGGACTGATTCATGGAGATGTACATGCCGGACATACTATGATTGATAAGGATGCCAATG
TGACTGGATTAATCGATTGGACTGAAGCGAAGGTTACAGATGTTTCGCATGACTTTATTTTCAACTATAGAGCTTTTGGG
GAAGAAGGGTTAGAAGCTTTAATTCTCGCTTATAAGGAAATTGGTGGATATTACTGGCCTAAAATGAAAGAGCATATTAT
CGAACTTAATGCAGCATACCCAGTTTCAATCGCTGAGTTTGCATTAGTGTCTGGAATTGAGGAATATGAGCAGATGGCAA
AGGAAGCATTGGAAGTACAAGGTTCGTAA

>CARD|phgb|AHEL01000071|3243-4143|ARO:3000318|mphB|MLS|Macrolide_phosphotransferases|MPHB
CTAGCGGTCATTCACTTCCAATGTTTCTTTCGCCATCTGCTCATATTCTTCCAAGCCTGAGATAATCGCAAACTCAGCTA
TCGCAACAGGGTATGCCGCATTAAGTTCAATGACGTGCTCTTTCATGGCAGGCCAGTAAATCCCACCTGCTTGCCGGTAA
TAGTTGATCAGTTTCTCCAGGGCTGCCTCCCCGAATACCCGGTACTGGAAAACAAAGTCATTTGATACATCCGTTACTTT
TGCTTCGGTCCAGTCGATAAAACCTGTTAAGTTAGCATCTTTATCAATCATCGTGTGGCCAGCATGAACATCCCCATGAA
TCAGACCTGTTCTCTGAGGCCACAATTCCTCATTTTTTACCCAGGCCTGCCAGCGGTTCCATAAGGATTCGCCTACGCCA
AACTTCGCTTTAACCTTTTTCATACGCTCAATCATCGATTTTCTTGCCTCTTCTGCTGTCTGGACAAACAGGCCTACTTT
AAGAGCCTCTGTTTTCGGAACTGTGTGTAGCGAAGCCAACGCTTTGGCTAATGTCTGGTGAAATTGTTCAGGCACATTTT
CATAATCCATCTCCCACACATAGTTTTGAATCTCCGGATCAATCGTGCCTGCTGGCACTCCGATTAACTTTTTATAAGCT
ATTAGATCGCCTTCATAAACCGACCAGACTGGAACCTGAAAAGTGGCATATTTATTTACAAGATCCAGTGCTTTCTTCTC
CACTATCGTCCTTGGCATCACATCGTCCCGTCTCGGAAACCTTAGCACCCATTCTTCGCCTTTATCGTCTTCTGCATAAG
CAACCAGAAAATCTAAACCGGACTCGTTGAATATGATGGACTCATCTTTAACTTCCAAACCATACTTTCTTGCTATTTCT
ACCGCTTTCTGTTTGTTCAAA