Resistance to macrolides can be mediated by hydrolysis of the macrolactone ring that is core to the structure of the macrolide antibiotics. The enzymes that perform this hydrolysis are known as macrolide esterases.

References

• PMID:22303981
• PMID:11810493
• PMID:15379732
• PMID:10582867

Other Mechanisms in MLS

Groups