MEGAResFrom MEG, the Microbial Ecology Group

ERMO

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

Other Groups in 23S rRNA methyltransferases

Sequences

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>MLS|ermO_2_AJ223970|MLS|23S_rRNA_methyltransferases|ERMO
ATGGCCCGCCCCACCCAGCGTGCGCGCACGCTCTCGCAGAACTTCCTCGCCGACCGCGCCGCCGCCGCACACGTCGCCCG
GCTGACCGCCCCCGACCGTCGGCACCCGCCGCTCGTCCTGGAAGTGGGCGCCGGCAAGGGCGCCCTCACCGAGCCGCTCG
CCCGCCGCAGCCGGGAGCTGCACGCCTACGAGATCGACTCCAGGCTCGTCCCCGGGCTGCGCACCCGTTTCGCCGCCGCA
CCCCATGTCCGCGTGGTCGCCGGTGACTTCCTCGCCGCGCGGCCTCCGCGCACGCCGTTCTCCGTCGCCGGGAACGTGCC
CTTCTCCCGCACGGCGGACATCGTCGACTGGTGCCTCGGCGCGCCGGCCCTCACCGACGCCACCCTGATCACCCAGCTCG
AGTACGCACGCAAACGCACCGGCGACTACGGCCGTTGGACCCTGCTGACGGTACGGACCTGGCCCCACCACGAGTGGCGC
CTGGTGGGACGCGTGAGCCGCTACGGCTTCCGGCCGGCGCCCCGCGTCGACGCGGGCGTCCTCCGTATCGAGCGCCGCGC
CACCCCGCTGCTCACCGGTGCCGCCCAGCACGGCTGGCGGGACCTGGTCGAGCTGGGCTTCTCCGGAGTCGGCGGCTCGC
TGCACGCGTCCCTGCGCCGGGCACACCCCAGGCGCCGGGTGGACGCGGCGTTCCGGGCGGCCCGGCTGGACCCCGGGGTG
CTCGTCGGCGAGGTGGCGCCGGCGCGGTGGCTGCGGCTGCACGAGGAGCTGGCGTCGTGA

>MLS|ErmO|M74717|40-822|783|MLS|23S_rRNA_methyltransferases|ERMO
ATGGCCCGCCCCACCCAGCGTGCCCGCACGCTCTCGCAGAACTTCCTCGCCGACCGCGCCACCGCCGAACGTGTGGCGCG
CCTCGCCGTCCCCGACCGGGGGCGCCCGCCCCTCCTGCTCGAAGTGGGCGCGGGCAACGGCGCCCTCACCGAGCCGCTCG
CCCGCCGCAGCCGCGAACTGCACGCCTACGAGATCGACCCCCGGCTCGTCCCCGGGCTCCGCGCCCGTTTCGCGCGCAGC
CCCCACGTCCACGTCGTCGCCGGTGACTTCCTCACCGCCCGGCCCCCGCGCACCCCGTTCGCCGTCGCCGGGAACGTGCC
CTTCTCGCGCACCGCCGACATCGTCGACTGGTGCCTGACCGCGCCCGGCCTCACCGACGCCACCCTCCTCACCCAGCTCG
AGTACGCCCGCAAACGCACCGGCGACTACGGCCGCTGGACCCTGCTCACGGTCCTGACCTGGCCGCGCCACGAGTGGCGG
CTGGTGGGCCGGGTGGGCCGCAGCCGCTTCTGCCCGGCGCCGCGCGTCGACGCCGGCATCCTCCGGATCGAACGCCGCCC
CACTGCGCTGCTCACCGGCGCCGCCGCCCGCCGCGACTGGGCGGACCTGGTCGAGCTGGGCTTCTCCGGCGTCGGCGGCT
CGCTGCACGCGTCCCTGCGCCGCGCCCACTCCCGGCGCCGGGTGGACGCGGCGTTCCGCGCCGCGCGGCTCGATCCCGGT
GTCCTCGTCGGCGAGGTCGCCCCCGACCGGTGGCTGCGGCTGCACGAGGAGTTGACGGCATGA