MEGAResFrom MEG, the Microbial Ecology Group

ERMH

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

Other Groups in 23S rRNA methyltransferases

Sequences

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>CARD|phgb|M16503|243-1143|ARO:3002823|ErmH|MLS|23S_rRNA_methyltransferases|ERMH
ATGGCTGCGCTCCTGAAGCGCATACTTAGGAGACGCATGGCTGAAAAGAGGTCAGGACGCGGGCGCATGGCCGCAGCGCG
TACAACCGGAGCTCAGTCGCGTAAAACGGCACAGCGGTCGGGCCGGAGTGAGGCTGACCGTAGAAGAAGAGTCCACGGGC
AGAATTTCCTCGTCGACCGGGAAACAGTACAACGGTTTGTGCGTTTCGCCGATCCGGACCCCGGGGAGGTCGTTCTCGAG
GTCGGTGCCGGTAATGGTGCGATCACGCGCGAGCTGGCGCGATTATGCCGACGAGTGGTGGCGTATGAGATCGACCGGCA
CTTCGCGGACCGATTACGTGAGGCGACCGCCGAGGATCCGCGGATCGAGGTCGTCGCCGGCGACTTCCTGAAGACCTCGC
AGCCCAAGGTCCCGTTCTCCGTGGTCGGCAACATCCCGTTCGGCAACACCGCGGACATAGTGGACTGGTGCCTGAACGCG
CGGCGGCTGCGTACGACCACCCTGGTCACCCAGCTCGAATACGCCCGCAAGCGCACCGGCGGCTATCGGCGCTGGTCACG
GCTCACCGTGGCCACCTGGCCCGAGGTGGAGTGGCGGATGGGCGAGCGGATCAGCCGCCGCTGGTTCCGGCCCGTCCCCG
CCGTCGACTCCGCGGTACTGCGACTGGAACGGCGACCGGTGCCGCTGATCCCACCCGGTCTGATGCACGACTTCCGGGAC
CTGGTGGAGACCGGGTTCACGGGAAAGGGCGGTTCGCTGGACGCCTCGCTGCGCCGGCGCTTCCCGGCCCGGCGGGTGGC
CGCCGGGTTCCGCAGGGCCCGCCTGGAGCAGGGCGTGGTCGTCGCCTACGTCACCCCGGGCCAATGGATCACACTCTTCG
AGGAACTCCACGGGCGCTGAC