MEGAResFrom MEG, the Microbial Ecology Group

ERM41

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

Other Groups in 23S rRNA methyltransferases

Sequences

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>936|EU590124.1|EU590124|MLS|23S_rRNA_methyltransferases|ERM41
GTGTCCGGCCAACGGTCGCGACGCCAGTGGGGCTGGTATCCGCTCACTGATGACTGGGCGGCGCGGATCGTCGCCGAATC
CGGTGTTCGCTCAGGGGAGTTCGTTGTGGATCTGGGCGCAGGACACGGCGCGCTGACGGCACATCTGGTTGCCGCTGGCG
CCAGGGTGCTAGCCGTCGAGCTGCATCCGGGGCGGGCTCGACACCTTCGTTCACGGTTTGCCGAGGAAGATGTCCGGATA
GCGGAAGCGGACCTGCTCGCCTTCCGGTGGCCGCGACGGCCATTTCGGGTGGTGGCGAGCCCGCCCTACCAAGTCACCAG
CGCACTGATCCGGAGTCTCTTGACGCCGGAATCCCGGCTGCTGGCTGCCGACCTGGTGCTGCAGCGCGGGGCTGTGCACA
AACATGCGAAGCGAGCACTTGTTCGCCATTGGACGCTACGGGCCGGAATCACATTGCCGCGAAGCGCTTTCCATCATCCA
CCGCAGGTGGATTCGTCGGTGCTGGTGATCAGGCGGCGCTGA