MEGAResFrom MEG, the Microbial Ecology Group

ERM37

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

Other Groups in 23S rRNA methyltransferases

Sequences

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>MLS|AE000516.2|gene2130|MLS|23S_rRNA_methyltransferases|ERM37
GTGTCCGCCCTCGGACGGTCGCGACGGGCATGGGGCTGGCACCGGCTCCATGACGAATGGGCAGCGCGGGTAGTCAGCGC
GGCCGCAGTGCGGCCCGGTGAGCTCGTGTTTGACATCGGCGCCGGCGAAGGGGCACTGACGGCGCATCTAGTGCGAGCGG
GGGCGCGGGTGGTCGCCGTGGAGTTGCACCCGCGACGAGTCGGTGTCCTCCGCGAGCGATTCCCTGGCATTACCGTGGTG
CACGCGGACGCCGCCTCGATCCGGTTGCCCGGCCGGCCGTTCCGGGTTGTGGCGAACCCGCCGTACGGGATTTCGTCCCG
CCTGCTGCGGACGCTGCTGGCACCCAACAGCGGGCTTGTCGCGGCCGATCTCGTGCTGCAGCGAGCCCTCGTATGTAAAT
TCGCTTCTCGCAACGCGCGAAGGTTCACCCTGACCGTCGGCCTCATGCTGCCACGGCGCGCGTTCCTGCCACCGCCGCAT
GTGGATTCCGCGGTGCTCGTCGTCCGCCGCCGGAAGTGCGGTGACTGGCAGGGGCGGTAA