MEGAResFrom MEG, the Microbial Ecology Group

ERM30

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

Other Groups in 23S rRNA methyltransferases

Sequences

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>MLS|Erm30|AF079138|1283-2293|1011|MLS|23S_rRNA_methyltransferases|ERM30
ATGGCAATGCGCGACTCCATACCGAGGCGAGCGGACCGCGACACCCTTCGCCGCGAATTAGGCCAGAACTTCCTTCAGGA
CGACAGAGCCGTGCGCAATCTCGTCACGCATGTCGAGGGGGACGGTAGGAACGTTCTCGAAATCGGCCCCGGAAAGGGCG
CGATAACCGAGGAGTTGGTGCGCTCCTTCGACACCGTGACGGTCGTGGAGATGGACCCGCACTGGGCCGCGCATGTGCGG
CGGAAATTCGAAGGGGAGAGGGTCACCGTATTCCAGGGTGATTTCCTCGACTTCCGCATTCCGCGCGATATCGACACCGT
CGTCGGAAACGTTCCCTTCGGCATCACGACCCAGATTCTCCGGAGTCTCCTGGAATCGACGAACTGGCAGTCGGCGGCCC
TGATAGTGCAGTGGGAGGTCGCCCGCAAACGCGCCGGTCGCAGCGGCGGATCGCTCCTCACGACCTCCTGGGCCCCCTGG
TACGAGTTCGCGGTCCACGACCGCGTCCGCGCCTCGTCGTTCCGTCCGATGCCCCGCGTCGACGGCGGCGTCCTGACGAT
CAGGCGACGCCCCCAGCCCCTGCTGCCCGAGAGCGCGAGCCGCGCCTTCCAGAACTTCGCCGAAGCCGTCTTCACCGGCC
CCGGACGGGGCCTCGCGGAGATCCTCCGGCGCCACATCCCCAAGCGGACCTACCGTTCCCTCGCCGACCGCCACGGAATT
CCGGACGGCGGACTGCCGAAGGACCTCACGCTCACCCAATGGATCGCCCTTTTCCAGGCCTCCCAGCCGAGTTACGCGCC
GGGGGCGCCCGGCACGCGCATGCCGGGCCAGGGCGGTGGCGCCGGCGGCAGGGACTATGACTCGGAGACGAGCAGGGCCG
CCGTGCCCGGGAGCCGCAGATACGGCCCCACGCGCGGCGGCGAACCCTGCGCACCCCGCGCACAGGTCCGGCAGACCAAG
GGCCGCCAGGGCGCGCGAGGCTCGTCGTACGGACGCCGCACGGGCCGTTAG