MEGAResFrom MEG, the Microbial Ecology Group

Notice: Trying to access array offset on value of type null in /home/meglabuser/megares.meglab.org/vendor/doctrine/annotations/lib/Doctrine/Common/Annotations/DocParser.php on line 967

ERM

Target modification is a common mechanism of resistance to antibiotics. The 23S methyltransferases transfer a methyl group to the 23S rRNA component of the bacterial ribosome, preventing the action of the MLS group of antibiotics.

References

  • http://cid.oxfordjournals.org/content/34/4/482.full

Notice: Trying to access array offset on value of type null in /home/meglabuser/megares.meglab.org/vendor/doctrine/annotations/lib/Doctrine/Common/Annotations/DocParser.php on line 967

Other Groups in 23S rRNA methyltransferases

Sequences

Download Sequences

>>MEG_2755|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGGCATTTTCCCCGCAGGGCGGCCGACACGAGCTCGGTCAGAACTTCCTCGTCGACCGGTCAGTGATCGACGAGATCGA
CGGCCTGGTGGCCAGGACCAAGGGTCCGATACTGGAGATCGGTCCGGGTGACGGCGCCCTGACCCTGCCGCTGAGCAGGC
ACGGCAGGCCGATCACCGCCGTCGAGCTCGACGGCCGGCGCGCGCAGCGCCTCGGTGCCCGCACCCCCGGTCATGTGACC
GTGGTGCACCACGACTTCCTGCAGTACCCGCTGCCGCGCAACCCGCATGTGGTCGTCGGCAACGTCCCCTTCCATCTGAC
GACGGCGATCATGCGGCGGCTGCTCGACGCCCAGCACTGGCACACCGCCGTCCTCCTCGTCCAGTGGGAGGTCGCCCGGC
GCCGGGCCGGCGTCGGCGGGTCGACGCTGCTGACGGCCGGCTGGGCGCCCTGGTACGAGTTCGACCTGCACTCCCGGGTC
CCCGCGCGGGCCTTCCGTCCGATGCCGGGCGTGGACGGAGGAGTACTGGCCATCCGGCGGCGGTCCGCGCCGCTCGTGGG
CCAGGTGAAGACGTACCAGGACTTCGTACGCCAGGTGTTCACCGGCAAGGGGAACGGGCTGAAGGAGATCCTGCGGCGGA
CCGGGCGGATCTCGCAGCGGGACCTGGCGACCTGGCTGCGGAGGAACGAGATCTCGCCGCACGCGCTGCCCAAGGACCTG
AAGCCCGGGCAGTGGGCGTCGCTGTGGGAGCTGACCGGCGGCACGGCCGACGGATCCTTCGACGGTACGGCGGGCGGTGG
CGCGGCCGGATCGCACGGGGCGGCTCGGGTCGGGGCCGGTCACCCGGGCGGCCGGGTGTCCGCGAGCCGGCGGGGCGTGC
CGCAGGCGCGGCGCGGCCGGGGGCATGCGGTACGGAGCTCCACGGGGACCGAGCCGAGGTGGGGCAGGGGGCGGGCGGAG
AGCGCGTGA

>>MEG_2756|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGACAAAAAAGAAATTGCCCGTTCGTTTTACGGGTCAGCACTTTACTATTGACAAAGTGCTTATTAAAGATGCAATAAA
AGAATCAAATATAAATCAACACGATACAGTTTTAGATATTGGAGCTGGTAAGGGTTTTCTAACTGTTCATCTCTTAAAAA
ATGTCGATAAAGTTATTGCCATTGAAAACGATGTTGCATTAAGTCAACATTTGCGCAAAAAATTCATTCACGCTCAAAAC
GTTCAAGTGGTTAGTTGTGATTATAGAAATTTTGTGGTTCCGAAAGTTCCATTTAAAGTAGTTTCAAATATTCCTTTTGG
TATTACATCTGATATTTTTAGTAGTCTGATGTTTGAAAATGTCGAATATTTTCTATGCGGTTCAATTATCCTTCAGTCAG
AACCGGCAAAAAAATTGTTTTCAAGTAAGGTTTATAACCCATTGACAGTACTTTATCATACCTATTATGATTTGAAATTC
CTGTATGAGATAAATCCTGAAAGTTTTTTGCCACCACCAACTGTCAAATCAGCACTTTTGAGAATTGAAAGAAAACAGAT
TTCATTAGATATTGGGCTTAAGGTTAAGTACTTAAATTTTGTTTCGTATATGTTACAAAAACCTGATTTAACAGTCAAAA
CAGCTATGAAGTCTATTTTTAGAAAAAAACAAGTTAGGTCAATTTCAGAAAAATTTGGAGTTGACCTTAACTCCAAAATT
GTCTGTTTGACTCCAAATCAATGGAAGAATTGTTTTTTAGAAATGCTCGAAGTTGTTCCTGAAAAGTTTCATCCGTCATA
A

>>MEG_2757|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGCCCACTTACCGTGGCGGCCGACATGAGCACGGCCAGAACTTCCTCACTGACCACACCACGATCGACCGGCTCTCACG
GCTGGTAGGCGACTCGACCGGTCCGATCGTCGAGATCGGCCCGGGCCAGGGCAGGCTCACAAGAGAGCTGCAGAAGCTCG
GCCGGTCCCTGACTGCTGTCGAGATCGACAGCCGGCTGGCGGACCGACTTGCATCGGCCAGTCAGTTCCGCGAGCAGAAA
CACGTAACCGTCGTCAACGCAGACTTCCTTCACTGGCCGCTACCGACCACTCCGTATGTGGTGGTCGGCAACGTTCCGTT
CCACCTGACCACAGCCATCCTGCGCAGACTGCTGCACGATGGAGCATGGACCCAGGTGGTCCTGCTCGTGCAGTGGGAAG
TGGCCCGCCGGCGTGCCGGCATCGGTGGTAGCAGCATGATGACCGCGCAGTGGTGGCCTTGGATCGACTTCAGCTTGCAC
GGGCGCGTGCCCCGGTCGGCGTTCAAGCCAGCCCCGAGCGTGGACGGTGGCCTCTTGGAGATGACTCGTCGTCCGGACCC
ATTGCTCAGCCCAGACGCGAGAGAGTCCTACCGACAGTTCGTCCATGACGTTTTCACCAGTAGGGGCAGGGGTATCGGCG
AGATCCTGGCTAACGTATCCAGCTCACTCGGAAAGCGGGGAGCGCTCCAGTTGTTGAAGAGCGAGGGGATTCGCTCCTCG
TCCCTGCCCAAAGATCTCTCAGCGGAGCAGTGGGCTCGCCTCTTTACCAGCGCGTCGCCTACGAAGAGTGCCAAAACCGG
AAGGAACGCACACCCCGCCCACTCCGCACGGCGGCAAGGTCGATGA

>>MEG_2758|Drugs|MLS|23S_rRNA_methyltransferases|ERM
GTGACATTGAAATCCCCACTGCCACCGCAATCCGTCTCCGCACCCGCTGATTCACGCAGCACCGCGCGGAGAGAATGGGG
TCAGAACTTCTTTCGTACAGCCGCCGCGGCCTGTCGTTTCTCCGCTCAGCTGGACGGTTCGGACACCATTCCGCCCGATT
CTCCGAATGACCTGATGACCGTCGAAATAGGCGCGGGATCAGGGCGGGTGACCAAAGTGCTCGCCTCACCCGGGACGCCT
TTACTCGCGGTGGAAATAGATCCCCGCTGGGCTCGGCGGCTGGCCGCCGAATCGCTGCCGGACGTCACGGTGGTGAACGA
GGATTTCCTGACCCTGCAACTGCCCGGGCAGCCGGTCAGACTCATCGGGAATCTTCCCTTCGTCACCGGCACCAGAATGC
TGAGGCGCTGCCTCGACATGGGTCCGGCGCGCATGCGGCAGGGCGTGTTCCTGTTGCAGCGGGAGTACGTGGGAAAGCGG
ACCGGAGCCTGGGGCGGAAACCTCTTCAACGCCCAGTGGGAGCCGTGGTACTCGTTCGACCGGGGCCTGGCCTTCTCACG
CCAGGACTTCACCCCCGTACCGCGCGCGGACACCCAGACCCTGATGGTCGCCCCGCACCGCAGGCCGTCCGTGCCCTGGC
GTGAGAAGGCCGCCTACCAGCGGTTCGTCCAACGGGTCTTCGACACCGGCCAGATGACGGTGGGCGACGCCGCGCGGAAG
GTGCTGCGCCGCGGACACGCCCAGTTCGTGCGCGGGGCGGGCGTGAGGCCGGCCGACCGGGTCAAGGACCTCACGGTCCC
GGAGTGGACCGCACTCTTCCGCGCCTACGGGCGGACGGCCGACCGCTGA

>>MEG_2759|Drugs|MLS|23S_rRNA_methyltransferases|ERM
GTGTCCACACCACATCACGGCCGGCACGAGCTCGGCCAGAACTTCCTGTCCGATCGGCGCGTCATCGCCGATATCGTCGA
AATCGTCTCGCGCACAAACGGTCCGATCATCGAGATCGGGGCGGGCGACGGCGCGCTGACCATACCCTTGCAACGACTCG
CCCGCCCGCTCACCGCCGTCGAGGTCGACGCGCGGCGCGCGCGGCGGTTGGCGCAGCGCACCGCGAGATCCGCCCCGGGG
CCTGCCTCGCGGCCCACCGAGGTCGTCGCCGCCGACTTCCTGCGCTACCCACTGCCCCGCTCACCCCACGTGGTCGTGGG
CAACCTGCCGTTCCACCTCACCACCGCGATCCTGCGGCGACTGCTGCACGGTCCGGGCTGGACCACGGCCGTGCTGCTCA
TGCAGTGGGAGGTGGCCCGCCGACGCGCCGCGGTGGGCGGCGCCACCATGATGACCGCCCAGTGGTGGCCGTGGTTCGAA
TTCGGCCTTGCCCGAAAGGTTTCCGCGGCGAGCTTCACGCCGCGGCCCGCGGTCGACGCCGGACTGCTCACCATCACGCG
CCGCAGCCGGCCGCTGGTCGACGTCGCGGACCGGGCGCGTTACCAGGCGCTGGTGCACCGCGTGTTCACCGGACGCGGAC
ACGGCATGGCGCAGATCCTGCAACGGTTGCCCACGCCGGTGCCCCGCACTTGGTTGCGGGCCAACGGGATAGCACCGAAC
TCCCTGCCCCGCCAGTTGTCCGCGGCGCAGTGGGCGGCGCTGTTCGAGCAGACGCGTCTAACTGGTGCCCAACGGGTCGA
TCGTCCACGCGATGTACAGCACGGCCGCGCTCACCGTCGCCGTGGTGGCGAAGTCGATCGCCCGGCTACGCACCACAAGC
AGACCGGCCCGGTCGTCGGTCAGCGCCAACCGCAGCGCGGCCGCGACGCCGACGCCGATCCCGATGACCAGCGCACCGCG
CCGCCAGTAACCCGCCACCACCAGGGCGAACGCCGCGATGAAGATCAGGCCGACCACCAGGATCGGCCATTGACCGGCGA
ACACCTTGCGGGCGAATTCCTTTGGCGTCACGCCAGTTTCGACTCTTCGGCTTCGACGACGTTGGTCAGCAGGAAGGCGC
GGGTCAACGGGCCCACGCCACCGGGGTTGGGCGACACGTGA

>>MEG_2760|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGACGAAAAAAATGAACAAGTATAATGGGAAAAAACTTAGCCGTGGAGAACCTCCCAATTTTAGCGGTCAGCATTTTAT
GCACAATAAACGGCTACTGAAGGAAATTGTTGATAAAGCTGACGTCTCTGTTCGTGATACGGTTTTAGAGCTGGGAGCAG
GAAAAGGCGCGTTGACGACGATTTTAAGCGAACGCGCGGACCGGGTTCTAGCCGTCGAGTATGACCAAAAATGTATTGAA
GCGCTGCAATGGAAACTAGTTGGGTCAAAAAACGTGTCCATTCTCCATCAAGATATTATGAAGGTGGCATTGCCAACGGA
ACCGTTTGTTGTTGTTTCCAACATCCCTTATTCGATCACAACGGCAATCATGAAAATGCTGTTAAACAATCCAAAAAACA
AACTACAACGAGGGGCAATTGTAATGGAGAAAGGAGCAGCAAAGCGGTTTACAAGCGTTTCGCCGAAAGACGCTTATGTG
ATGGCTTGGCATATGTGGTTTGACATCCACTATGAAAGGGGAATTTCCAGAAGTTCATTTTCGCCGCCGCCGAAAGTCGA
TTCTGCCCTTGTCCGCATTGTCCGCAAACAGCATCCCCTTTTTCCATATAAAGAGGCGAAAGCGATGCATGACTTTTTAT
CGTACGCACTAAACAACCCTAGAGCACCCCTTGATCAGGTATTACGAGGAATTTTTACCGCCCCTCAAGCAAAAAAAGTG
CGGCAGGCAATCGGCGTCAAACCTGAGACACCAGTGGCCATGCTTCATGCCAGGCAGTGGGCGATGGTTTGTGACGCGAT
GGTTCGGCATGTTCCAAAAGTGTATTGGCCAAGGCGAAAGAGATAA

>>MEG_2761|Drugs|MLS|23S_rRNA_methyltransferases|ERM
GTGTCTTCAGTTCATCACGGCCGGCATGAGAACGGCCAGAATTTTCTGCGCGACCGTCGAGTGGTCGGCGACATCGTGAG
GATGGTCTCGCACACAGCGGGTCCCATCGTCGAGATCGGGGCCGGAGACGGCGCCCTCACCCTGCCGTTACAGCGGCTGG
GCCGACCGTTGACCGCCATCGAGATCGACCTCCACCGTGCCCGACGGCTCGCCGACCGAACCACTGCCGAGGTGATCGCA
ACCGACTTCCTGCGGTACCGGCTGCCGCGCACGCCGCACGTGGTGGTGGGCAACCTGCCGTTCCATCTGACCACCGCCAT
CCTCCGGCGCCTACTGCACGAGAACGGCTGGACCGATGCGATCCTGTTGGTGCAGTGGGAGGTGGCTCGACGGCGGGCCG
GTGTCGGCGGCGCCACCATGATGACCGCCCAGTGGTGGCCGTGGTTCGAATTCGGCCTGGCGCGAAAGGTTTCGGCCGAC
GCGTTCCGGCCGCGGCCGAGTGTGGATGCCGGGCTGCTGACCATTCAGCGCCGAGCTGAGCCGCTACTCCCGTGGGCCGA
CCGTCGTGCGTATCAGGCGCTGGTCCACAGGGTTTTCACCGGGCGCGGGCGTGGTCTGGCCCAGATTCTGCGGCCCCACG
TGCACCCACGGTGGCTGTCTGCCAACGGAATTCACCCGTCGGCTCTGCCCAGAGCGCTGACGGCTCGACAGTGGGTGGCG
TTGTTCGATGCCGCCGGCTAG

>>MEG_2762|Drugs|MLS|23S_rRNA_methyltransferases|ERM
GTGTCATCCAAAAATCAAGGCCGGCATGAGCACGGCCAGAATTTTCTGTGCGACCGTCGCGTGGTCGCCGACATCGTCAA
AATCGTCTCGCACACAACAGGTTCCATCGTCGAGATCGGCGCCGGAGACGGTGCGCTGACCGTCCCGATGCAGCGGCTCG
GGCGGCCGTTGACGGCCATCGAGATCGACCGTCGACGAGCAGAGCGCCTGGCTCGCCGTACCACGGCGCATGTCGTCACC
GCCGATTTCCTGCGCTACCGCCTGCCACCCACCGAGCACGTGGTGGTGGGCAACCTGCCGTTCCACCTGACCACCGCGAT
TTTGCGGCGGCTGCTGCACAGCCCGGCATGGACCGACGCGGTGCTGCTCATGCAGTGGGAGGTGGCGCGCCGCCGCGCCG
CGGTCGGCGGCGCAACGATGATGACCGCGCAGTGGTGGCCGTGGTTCGAATTCGGCTTGGCCCGTAAGGTTTCCGCCGAC
GCGTTCCGTCCCCGCCCGAGCGTGGACGCCGGGTTGCTGACCATCACGCGGCGCCGGGAACCGCTGATCGACGGCGCCGA
CCGCCGGCGCTACCAGGCGCTGGTCCATGCAGTGTTCACCGGGCGCGGCCGCGGTGTGGCGCAGATTGTGGGTCCACGAG
TCCCGCGGCACTGGTTGCGCCACAACGGCATCACACCGTCGGCGCTGCCGAGGGATCTCACGGCCGCGCAGTGGGCAGCT
CTGTTCGAGGTGACGAGCGAGGCGAAGCGGTGCTAG

>>MEG_2763|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGTCATCAATCCGGCGCCGGCACGCCGCCGCTTCGCTCGACACCCCTGCCGTGGGCGGCAGGCACGAACTCGGTCAGAA
CTTCCTCGTCGACCGAGGTGTATGCACAAGGATCGCCGAGGTCGTCTCCTCGACGACGGCCCATCCGGTCCTCGAACTGG
GCGCCGGTGACGGTGCCATCACCCGGGCCCTGGTCGCGGCGAATCTCCCGGTCACCGCGCTGGAACTCGACCCCCGGCGG
GTCCGGCGGCTCCAGCGGACCTTCGCCGACGGGGTCACCGTCGTGCACGGGGACATGCTCCGGTACGACTTCGGGCCGTA
CCCGCACCACGTGGTGTCGACCGTGCCGTTCTCCATCACCACGCCGCTGCTCCGGCGCCTGATCGGCCAGCGGTTCTGGC
ACACCGCGGTGCTGTTGGTGCAGTGGGAGGTGGCCCGTAAGCGGGCCGGTGTGGGCGGCACCACGATGCTCACCGCAGCC
AGTTGGCCGTGGTACGAGTTCACCCTGGTGGAGCGGGTGCCGAAGACCTCGTTCGACCCGGTGCCGAGCGTCGACGGCGG
CATCCTCGTCATCGAGCGTCGATCCGCGCCGCTGCTCGACGACCGCTGCGTGGGTGACTACCAGAACCTGGTACGCGAGG
TGTACACCGGTCCCGGTCGTGGTCTGGCCGCGATTCTCCGTACCCGTCTGCCCGGTCGTGAGGTGGACGCCTGGCTCCGC
CGCGAGCGGGTGGACCCGGCGGCCCTGCCCCGCGACCTCAAGGCCGGGCACTGGGCATCCCTCTACCGGCTCTACCGGGA
GGTGGGTACTCGGCCCGCCCCTGCCGGCCGGTCCGTCCGGGCCCGGCCCGGATCCGTCGGCCCCGACCGCTCGCTCCCTC
CGCGCGGCCTGCGATCCGGTCCGCCGAGGGCTCGACGACGTGGTGGAGGCGCCTGA

>>MEG_2764|Drugs|MLS|23S_rRNA_methyltransferases|ERM
GTGGATCTGGGCGCAGGACACGGCGCGCTGACGGCACATCTGGTTGCCGCTGGCGCCAGGGTGCTAGCCGTCGAGCTGCA
TCCGGGGCGGGCTCGACACCTTCGTTCACGGTTTGCCGAGGAAGATGTCCGGGTAGCGGAAGCGGACCTACTCGCCTTCC
GGTGGCCGCGACGGCCATTTCGGGTGGTGGCGAGCCCGCCCTACCAAGTCACCAGCGCACTGATCCGGAGTCTCTTGACG
CCGGAATCCCGGCTGCTGGCTGCCGACCTGGTGCTGCAGCGCGGGGCTGTGCACAAACATGCGAAGCGAGCACCTGTTCG
CCATTGGACGCTACGGGCCGGAATCACATTGCCGCGAAGCGCTTTCCATCATCCACCGCAGGTGGATTCGTCGGTGCTGG
TGATCAGGCGGCGCTGA

>>MEG_2765|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGAATAACAAAAATCCCAAAGATACGCAGAACTTTATAACCTCTAAGAAATGTATAAATGAAATATTAAAAAATATTAT
TATTACAGCAGATGATAACATTGTTGAAATTGGAACTGGGAAAGGTCATTTTACGAAAGCTTTATCAAAAGTAGTTAAGT
CTGTAATTGGCGTAGAAATCGATAAGTCTTTATATTATAACTTGAAAAAGGATAGTAAACTACAAGATAATATACAACTT
ATTAATCAAGATATATTAAATTTTCAATTCCCTGATAATAAAGATTATAAAATTTTTGGTAGTATTCCTTATAATATTAG
TACTGAAATTATTAAAAAAATACTGTATGAGAGTAAAGCAGAATACAATTATTTAATTGTAGAATTAGGATTTGCTAAAC
GGATTCAAGATAAAAATAAAGCGTTAAGCCTACTATTATTGCCTAAAATGGATGTTGAAATCTTGAAAGTAATTCCTAAC
AAATATTTTCATCCCAAACCTAAAGTAGAATCGGCATTAATATTATTAAAAAAACATAAACCTTTAATTTCGGCAAAAGA
TGAAAAAAATTATCAATTCTTTGTATATAAGTGGGTAAACAAAGAATATAAGAAATTGTTTACAAAAAACCAGTTTAAGA
AAGCATTAAAAAATGCAAATGTACAAAACTTAAATAAAATATCGAAACAACAATTTATCTCTATTTTTTATAGTTATAAA
TTATTTAATTAA

>>MEG_2766|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGAATAACAAAAATCCTAAAAACTCACAAAATTTTATAACATCTCAAAAGCATATTAACGAGATATTAAATGAAACAAA
CATAGGCATTGATGATAATATAATTGAAATTGGAACTGGAAAAGGACACTTTACAAAATACATGTCCAATATAGCTAGAT
TTATAACTAGTATAGAAATTGACAAGGCTTTATATTGTAATTTGAAAAATGATATTAGTTTGTCAACTAATATTGAATTA
GTGAATAAAGATATACTGATATATGAGTTTCCTAAATACAAGCAGTATAAAGTTTTTGGTAGCATCCCATATAATATAAG
TACTGAAATAGTCAAAAAAATCTTATATGAAAGTAATGCTGAATATAACTATCTTATTGTAGAATTCGGATTTGCTAAAC
GAATTATGGATAAAAAAAGAGCGTTAGCCTTATTACTTTTACCTAAAATTGATATTGAAATTTTAAAAGTAATTCCCAAC
TCTTATTTTCATCCTAAACCTAAAGTAGATTCAGCGTTAATCTTACTAAAGCAGCACAAATCTTTAATCTCAAAAAATGA
TGAAAATGCATATCATTTTTTTGTATATAAATGGATAAACAAAGAATATAAACAGCTATTTACAAAGAATCAGTTTAATA
AAGCGTTAAAACATGCAAAGGTACAGAATATAAATGAAATATCAAAAGAACAATTTATATCAATTTTTCATAGTTATAAA
TTGTTTAATTAA

>>MEG_2767|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGCCTACCTACCGTTCCGGCCGTCACGAGCTCGGCCAGAACTTCCTCACGGACCGCAAAGCAGTCGATACGATCGTCGA
CCTCGTTTCTCGAACAGACGGCCCGATCATCGAAATCGGCTCCGGCGGTGGGGCGTTGACATTGCCCCTGCAGGCGCTGC
GTCGACCGATCACAGCTATCGAGATCGATCCGCGACATGTGCAAAAGCTCCAACATCGCGTCGATCCGAGTACGACGGTC
GTGCACGGCGACTTCCTGCGCTACCGACTGCCCCGAACACCGCACACCATCGTGGGGAACTTGCCGTTCCACCACACCAC
GGCGATGTTGCGGCGAATCCTCCACGCCGAACACTGGACAGCGTCGGTCCTGCTCGTGCAGTGGGAGGTTGCACGTCGTC
GTGCGGCGGTCGGTGGCGCAACGATGATGACTGCGCAATGGTGGCCGTGGTACGACTTCGGCCTGGCCGGCCGTGTTTCC
GCATCGGCGTTCACACCACGGCCGGGAGTCGATGCAGGGCTGATGACCATCGCTCGGCGGACCGTTCCACTCGTCGACCC
CGCGCTACGTCCCCGATACAGCACCTTCGTCCACACCGTCTTCACCAGCAAGGGCCACGGCCTGCATCAGATCTTGCCGC
GGGTGGCTGGCGATCCTGAGAAGGCCGCGGTTAAGAAGTGGCTCGCTGGCCAGCGATTTCGAGGCACACCGCTGCCGCGC
GACCTCTCACCCGGACAATGGTCCGAGCTCTTCGCGATCATCGATCGACGCTCTCCGGCTACCGATCGGAAGCGGGCTGA
GTACCGGCGATGA

>>MEG_2768|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGAACAGAAAAAGTGTTAGATTTGGACAAAATTTTGTAACTTCTATTAATGATATAAACAAAATATGTAAGAAGATAGA
CGTGAATTCTAATGATGTTTATTTTGAAATTGGTCCAGGTAAAGGGCATTTTACTCAATACTTTGTGGAAAGGGCTAAAG
AGGTAATTGCTATTGAAATAGACAGTGAATTAATTCCTATATTAAACAACAAATTTTCAGATCTAGATAATATAAAAATT
ATTAATCATGACTTTATGTCTTATGAATTACCATCTACATTTAAGTATAAAGTTTTTGGAAATATTCCATTTAATTTGAG
TACTTCTATTATTCGTAAACTTAGTTTAGAAAAATATGCAGATGAGATTTACTTAATAGTGGAATTAGGGTTTGCAAAAA
GATTAGAAGACTTAAACCGTAAAATGGGACTAATGTTAGCTCCATTTTATGAAATTTCAATTTTATACAATATTCCAAAA
AGATATTTTCATCCCATACCCAGTGTTGAGGTAGTGCTGATAAAACTAAAAAGAACTTCCTATAATATGTCCATGAAAGA
ATATATAAAGTATGAAGACTTTATAGAAAAATGGGTAAAAAAGGATTATAATGTTTTATTTACAAAAAATCAGCTAAAAC
AAGCAATCAGATATGGAAATATTGATAATTTAAGAATCCTAAAAGTTGATCAAATTCTATCCATATTTGAAAGTTACAAA
TTATTTAATGGGTTAAAGTAA

>>MEG_2769|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGATAAATAAGGAGCAGAATATAATGGATAATAGAAATTCTAAAAACTCACAGAACTTTATAACATCCCGAAAATATAT
CAATGATATATTAAAAGAAACAAGCATAGGCGCTGATGATAATATAATTGAAATTGGAACTGGAAAAGGACATTTTACAA
AGCAATTATCTAATATTGCTAGATTTGTAACTGGCGTAGAAATTGATAAGTCTTTATATCGTAATTTAAAAAAGGATATT
GAATTGTCCAATAATGTCGAATTAGTGAACAAAGATATATTGAAGTATCAGTTCCCTAAATGTAAAAAGTATAAGGTTTT
TGGTAATATACCATACAATATAAGTACTGAAATAGTTAAAAAAATCTTATATGAGGGGAATGCTGAATATAATTACCTTA
TTGTAGAATATGGTTTTGCTAAACGAATTATGGATAAACGAAGAGCACTAGGTCTATTACTTTTGACTAAATTAGATGTT
GAAATATTAAAAGTAATTCCCAACACTTATTTTCATCCTAAACCTAGAGTAGAATCGGCATTAATCTTATTAAAGCAGCA
CAAATCTTTAATCCAAAAAAGAGACGAAAAATTATATCAATTTTTTGTGTATAAATGGGTAAATAAAGAGTATAAACAAT
TATTTACAAAAAATCAGTTTAATAAGGCGTTAAAAAATGCTAAAGTAAAAAATATAAATGAAATGACAAATGAACAATTT
ATATCAATTTTTCATAGTTATAAATTGTTTAATTAA

>>MEG_2770|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGAATCAAAATATTAAGTTTACTCAAAATTTTATTACAAACGAAAAATTATTATCTAATATAATGAAACAAATAAATAT
AGATGAGAATGACATAATTTATGAGGTTGGAACTGGTAAAGGTCATCTGACCTCTAAATTAGCAGAAAAATGTAAGCATG
TTTATTCAATAGAGTTAGATAAAAAATTATATGAACTTTCTTCGAATAAGTTACAAGATAATAGTAGAGTTACTCTAATC
AATCAAGATATTTTACAATTCAATTATCCGTATAGAAAAAAATATAAGATAGTTGGTAACATACCATTCAATATAAGTAC
TCAAATCGTGAAAGATGCAGTATTTAGAAGCCAAGCTTCTGAGATGTATTTTATTGTAGAAGAAGGTTTCTACAAAAGAA
TGATAGATACTCGTAGAACTCTAAGTTTGCAACTACAAACACAGGTTTATATACAACAATTGTTACCTATACCTGCTGGA
AGTTTTCACCCAAAGCCAAAAGTAAATTGTATTTTAATAAAACTTACAAGACACATATCAGATATAAAAGATAAACATAA
GAAAAAATATGAGTTTTTTATATCAAAGTGGGTTAATAAAGAGTATTCAAAATTATTCACTAAAAATCAGTATCATCAAG
CATTGAAACATGCAAGGATAAAAGACCTTAATAAAATAAGTTATGAACAAGTATTATCAGTTTTTGAAAGTTATATATTA
TTCAATCCACGAAAATAA

>>MEG_2771|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGAATAACAAAAACCCAAAAGATTCACAAAATTTTATAACATCTCAAAAATATATAAATGAAATCTTACAAAATACTAA
TATAGAATCAAATGACAATATCATTGAAATAGGAACAGGCAAGGGGCATTTTACAAAAGCATTATTAAAAATATCTCACT
TTGTAACTGGAATAGAAATTGATAGGAATTTGTATTATAAATTAAAAAAAGACACTGACCTATATGATAATCTTAAATTA
ATCAATAAAGATGTATTGAGATTCCAATTTCATCAAAATGAACCTTATAAGATTTTTGGGAGTATTCCCTATAATATTAG
TACAGAAATAATTAAAAAGATTTTGTATGAAAGTAAGTCAGAATTTAACTATCTAATTGTGGAGCTAGGATTTGCTAAAC
GTCTCTTAAATAAAAAAAGAGCGCTAAGTTTATTATTATTACCTAAAATGGATGTTGAAATTTTAAAAATAATCCCTAAC
GTTTATTTCCATCCTAAACCAACAGTAGATTCGGCACTAATTTTATTAAAACGACATAAGCCTTTAGTTTCAGAGAAAGA
TGAAAAGATATATCATTTTTTTGTATATAGATGGGTGAACAAAGAATATAAGAAACTGTTTACCAAAAATCAATTTAATA
AAACATTGAATCATGCAAATGTGCAAGACATCAATGAATTATCAAAAGAACAATTTATATCTATTTTTAATAGTTATAAA
TTGTTTAATTGA

>>MEG_2772|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGAGAAATATTAAGGACACTCAAAATTTTTTACATAGCAAGGAGCTAGTTAGGCACTTAATAGGAATCTGTAATATAAA
GTTGGACGATGTGGTTATAGAAATTGGTCCTGGAAAAGGAATAATTACTAACGAATTAGCTCATAAAGCAAGAAAGGTTG
TTGCCATTGAATTTGATGAAGAACTATACGAAAAGCTAAAAAACAAATTTCAAAGCAACAATAAAGTTGACATAATTTAT
GGGGATATTTTAAACTATACTCCTAGAATTCCTAGTTATTGCGTTTTTTCAAACATTCCATTTAACATTACCTCTGAAAT
ACTAAATAAGTTTTTGAGCGACAAAAAGAATGAGAAAATGTTTTTAATAATGCAATATGAGCCATTTATAAAATACGCAG
GTAATCCATACGGAGCTGAAACATTAAGATCAATGCTTTATAAACCATTTTTTGATATGGATTTAAAATATAGATTCGAT
CCGTCTGATTTTAAGCCAGCACCACAAGCAAGAATCGTTTTGGCTTCCTTTGAAAGAAAGCAATTTCCTGATGTTAAAAA
GGAAGAGGAAAAACTATATAAAGATTTTCTTGCATATATTTATACTAACAAGGGTGAAACATTCTTTGCAAAGATTAAAA
CATTGTTTTCAAGCAATCAAATTAAACGAGTTTGGGGTCAGATTAAGATAGACAAGACAACAAAAATAAGCGAAGTACCA
TATGAATCAATTTTAAAGGTTTTTAAGCTTTTTTTCTTGTACGGAACAGATGCTAATAAACAGTTAGTTGTAAATTCATT
TAACAATATGAACAAGCAAAATAACAAGCTTCAAAAAAATCACAGAAACAATAGCAAGGCAAAAAGTTGGAATTCAAATC
GTAAAAGAAAGCCTTATCATAGAAATAATGTATAA

>>MEG_2773|Drugs|MLS|23S_rRNA_methyltransferases|ERM
ATGACGAAAAAGAAGCATAAATACAGCAATAAAAAACTTAGTCGCGGAGAGCCCCCCAATTTCTCCGGTCAGCATTTAAT
GCATAATAAAAAGCTACTGCAAGAAATTGTGGATCAGGCAAAGGTTAGTAAAAAAGATACCGTATTAGAGCTCGGCGCTG
GCAAAGGGGCGTTGACGACGTTTCTTAGTGAACGAGCGAAAAGAGTGCTCGCAGTGGAATATGACCAAACGTTTATTCAA
GTGTTAAACCGGAAAATGGCGCACGCCGCCAATACGACGATCATACACGAGGACATTATGCGCATTCATTTACCTAAGGG
GGAATTTGTCGTCGTTTCCAATATCCCATATTCGATTACGACGCCAATTATGAAAAAGCTTCTTTCCAATCCGGTAAGTG
GTTTTCAACGAGGTGTGATCGTGATGGAAAAAGGAGCAGCGAAACGGTTCACGTCGCCTTTCATCAAAAATGCATATGTG
CTCGCATGGCGGATGTGGTTTGACTTGGAGTACGTCAAAGGGATTTCGAGAGAGTGTTTTTCACCTCCTCCAAAGGTGGA
TTCGGCGATGGTATTCATTTCTCGCAAGCCGGACCCAATTGTACCGTATAAGGATCGCTCCGCCTTTTTCGGTCTAGCAG
AATATGCGCTCCGCGAGCCTAAGGCGCCAGCTGATTCACTGCTACGAGGGATTTTTACAGCTACACAATTAAAACATGTG
AAGCGCAATGCTGGGATTAAGCACGATGTCTCAATTGGTGCATTATCGGAAAGGCAATGGGGCGTCATCTTTGAAACCAT
GACTCAATATGTAAGACGGCCGCTGTGGCCACGACCGAGAAAGACAACATTATAA