MEGAResFrom MEG, the Microbial Ecology Group

VanM-type accessory protein

The vancomycin resistance gene clusters contain three general categories of genes, the core resistance proteins (VanHAX), the accessory proteins (VanJKWYZ and MurF2), and the sensor-regulator genes (VanRS). The accessory proteins are not essential for resistance but are known to enhance resistance in some bacteria. Other accessory genes, such as vanW, have unknown function at this time. The VanM resistance cluster is similar to VanA in sequence identity and VanD in organization. Its terminal product is D-ala-D-lac.

References

Other Mechanisms in Glycopeptides

Groups

Sequences

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