MEGAResFrom MEG, the Microbial Ecology Group

Fosfomycin thiol transferases

Thiol transferases specific for fosfomycin cause fosfomycin resistance by creation of an adduct between the fosfomycin molecule and glutathione or L-cysteine, rendering the antibiotic ineffective.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/2193621

Other Mechanisms in Fosfomycin

Groups

Sequences

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