MEGAResFrom MEG, the Microbial Ecology Group

QNRS

The Qnr peptides bind to the topoisomerases and directly prevent the action of the fluoroquinolone class of antibiotics.

References

Other Groups in Quinolone resistance protein Qnr

Sequences

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>CARD|phgb|KF732714|0-657|ARO:3002798|QnrS9|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTTCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>Flq|QnrS6_1_HQ631376|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACCGTCACACATATCGACACCACAGTTTTTCACATCAAGATCTAAGTGATATTACTTTCACTGCTTGCAC
CTTTATCCGATGCGATTTTCGACGTGCTAACTTGCGTGATGCGACATTTATTAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGTTGCCATTTTGATGTCGCAGACCTTCGCGATGCAAGTTTCCAACAATGCCAGCTTGCGATGGCAAACTTTAGT
AACGCCAATTGCTACGGTATTGAGTTACGTGAGTGTGATTTAAAAGGGGCCAACTTTTCCCGAGCAAACTTTGCCAATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCCTTTATTACTGGATGTAACCTGTCTTATGCCAATATGGAGCGGGTCTGTT
TAGAAAAATGTGAGCTGTATGAAAATCGCTGGATAGGGACTCACCTCGCGGGCGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCTGAAGATGTCTGGGGACAGTTTAGCCTACAGGGTGCTAATTTATGTCACGCCGAACTCGACGGTTT
AGATCCTCGAAAAGTCGATACATCAGGTATCAAAATTGCCAGCTGGCAACAAGAACAGCTTCTCGAAGCGTTGGGTATTG
TTGTTTTTCCTGACTAG

>Flq|QnrS2|DQ485530|1-657|657|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACCGTCACACATATCGACACCACAGTTTTTCACATCAAGATCTAAGTGATATTACTTTCACTGCTTGCAC
CTTTATCCGATGCGATTTTCGACGTGCTAACTTGCGTGATGCGACATTTATTAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGTTGCCATTTTGATGTCGCAGACCTTCGCGATGCAAGTTTCCAACAATGCCAGCTTGCGATGGCAAACTTTAGT
AACGCCAATTGCTACGGTATTGAGTTACGTGAGTGTGATTTAAAAGGGGCCAACTTTTCCCGAGCAAACTTTGCCAATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCCTTTATTACTGGATGTAACCTGTCTTATGCCAATATGGAGCGGGTCTGTT
TAGAAAAATGTGAGCTGTTTGAAAATCGCTGGATAGGGACTCACCTCGCGGGCGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCTGAAGATGTCTGGGGACAGTTTAGCCTACAGGGTGCTAATTTATGTCACGCCGAACTCGACGGTTT
AGATCCTCGAAAAGTCGATACATCAGGTATCAAAATTGCCAGCTGGCAACAAGAACAGCTTCTCGAAGCGTTGGGTATTG
TTGTTTTTCCTGACTAG

>Flq|QnrS3|EU077611|1-657|657|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
TGGAAACCTACAATCATACATATCGGCACCGCAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCACA
TTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATAT
CGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGTA
ATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCAA
GTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTTT
AGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGTC
GAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTTA
GATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTGT
TGTTTATCCTGACTAA

>Flq|KF730652.1|gene1|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ACTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>Flq|KF730651.1|gene1|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCATGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>Flq|Qnr-S5|HQ631377|1-657|657|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACCGTCACACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGCTCTCACCTTCACTGCTTGCAC
ATTTATTCGCAGCGACTTTCGACGAGCTAACTTGCGCGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTGGCGATGGCAAACTTCAGT
AACGCCAATTGCTACGGTATTGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCCTTTATTACAGGATGTACTCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAGATGTGAGTTGTTTGAAAATCGCTGGATAGGAACTCATCTAGCGGGTGCATCATTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTAGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCTTGGCAGCAAGAACAGCTTCTCGAAGCACTGGGTATTG
TTGTTTTTCCTGACTAG

>Flq|QnrS|FJ418153|1-657|657|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGCCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>Flq|Qnr-S1|AB187515|9737-10393|657|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA