MEGAResFrom MEG, the Microbial Ecology Group

QNRS

The Qnr peptides bind to the topoisomerases and directly prevent the action of the fluoroquinolone class of antibiotics.

References

  • http://cid.oxfordjournals.org/content/41/Supplement_2/S120.full

Other Groups in Quinolone resistance protein Qnr

Sequences

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>>MEG_6017|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
atggaaacctacaatcatacatatcggcaccacaacttttcacataaagacttaagtgatctcaccttcaccgcttgcac
attcattcgcagcgactttcgacgtgctaacttgcgtgatacgacattcgtcaactgcaagttcattgaacagggtgata
tcgaaggctgccactttgatgtcgcagatcttcgtgatgcaagtttccaacaatgccaacttgcgatggcaaacttcagt
aatgccaattgctacggtatagagttccgtgcgtgtgatttaaaaggtgccaacttttcccgaacaaactttgcccatca
agtgagtaatcgtatgtacttttgctcagcatttatttctggatgtaatctttcctatgccaatatggagagggtttgtt
tagaaaaatgtgagttgtttgaaaatcgctggataggaacgaacctagcgggtgcatcactgaaagagtcagacttaagt
cgaggtgttttttccgaagatgtctgggggcaatttagcctacagggtgccaatttatgccacgccgaactcgacggttt
agatccccgcaaagtcgatacagcaggtatcaaaattgcagcctggcagcaagaactgattctcgaagcactgggtattg
ttgtttatcctgactaa

>>MEG_6018|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
atggaaacctacaatcatacatatcggcaccacaacttttcacataaagacttaagtgatctcaccttcaccgcttgcac
attcattcgctgcgactttcgacgtgctaacttgcgtgatacgacattcgtcaactgcaagttcattgaacagggtgata
tcgaaggctgccactttgatgtcgcagatcttcgtgatgcaagtttccaacaatgccaacttgcgatggcaaacttcagt
aatgccaattgctacggtatagagttccgtgcgtgtgatttaaaaggtgccaacttttcccgaacaaactttgcccatca
agtgagtaatcgtatgtacttttgctcagcatttatttctggatgtaatctttcctatgccaatatggagagggtttgtt
tagaaaaatgtgagttgtttgaaaatcgctggataggaacgaacctagcgggtgcatcactgaaagagtcagacttaagt
cgaggtgttttttccgaagatgtctgggggcaatttagcctacagggtgccaatttatgccacgccgaactcgacggttt
agatccccgcaaagtcgatacatcaggtatcaaaattgcagcctggcagcaagaactgattctcgaagcactgggtattg
ttgtttatcctgactaa

>>MEG_6019|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
TGGAAACCTACAATCATACATATCGGCACCGCAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCACA
TTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATAT
CGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGTA
ATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCAA
GTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTTT
AGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGTC
GAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTTA
GATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTGT
TGTTTATCCTGACTAA

>>MEG_6020|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6021|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACCGTCACACATATCGACACCACAGTTTTTCACATCAAGATCTAAGTGATATTACTTTCACTGCTTGCAC
CTTTATCCGATGCGATTTTCGACGTGCTAACTTGCGTGATGCGACATTTATTAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGTTGCCATTTTGATGTCGCAGACCTTCGCGATGCAAGTTTCCAACAATGCCAGCTTGCGATGGCAAACTTTAGT
AACGCCAATTGCTACGGTATTGAGTTACGTGAGTGTGATTTAAAAGGGGCCAACTTTTCCCGAGCAAACTTTGCCAATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCCTTTATTACTGGATGTAACCTGTCTTATGCCAATATGGAGCGGGTCTGTT
TAGAAAAATGTGAGCTGTTTGAAAATCGCTGGATAGGGACTCACCTCGCGGGCGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCTGAAGATGTCTGGGGACAGTTTAGCCTACAGGGTGCTAATTTATGTCACGCCGAACTCGACGGTTT
AGATCCTCGAAAAGTCGATACATCAGGTATCAAAATTGCCAGCTGGCAACAAGAACAGCTTCTCGAAGCGTTGGGTATTG
TTGTTTTTCCTGACTAG

>>MEG_6022|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
TGGAAACCTACAATCATACATATCGGCACCGCAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCACA
TTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATAT
CGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGTA
ATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCAA
GTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTTT
AGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGTC
GAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTTA
GATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTGT
TGTTTATCCTGACT

>>MEG_6023|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGCCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6024|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACCGTCACACATATCGACACCACAGTTTTTCACATCAAGATCTAAGTGATATTACTTTCACTGCTTGCAC
CTTTATCCGATGCGATTTTCGACGTGCTAACTTGCGTGATGCGACATTTATTAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGTTGCCATTTTGATGTCGCAGACCTTCGCGATGCAAGTTTCCAACAATGCCAGCTTGCGATGGCAAACTTTAGT
AACGCCAATTGCTACGGTATTGAGTTACGTGAGTGTGATTTAAAAGGGGCCAACTTTTCCCGAGCAAACTTTGCCAATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCCTTTATTACTGGATGTAACCTGTCTTATGCCAATATGGAGCGGGTCTGTT
TAGAAAAATGTGAGCTGTATGAAAATCGCTGGATAGGGACTCACCTCGCGGGCGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCTGAAGATGTCTGGGGACAGTTTAGCCTACAGGGTGCTAATTTATGTCACGCCGAACTCGACGGTTT
AGATCCTCGAAAAGTCGATACATCAGGTATCAAAATTGCCAGCTGGCAACAAGAACAGCTTCTCGAAGCGTTGGGTATTG
TTGTTTTTCCTGACTAG

>>MEG_6025|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACCGTCACACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGCTCTCACCTTCACTGCTTGCAC
ATTTATTCGCAGCGACTTTCGACGAGCTAACTTGCGCGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTGGCGATGGCAAACTTCAGT
AACGCCAATTGCTACGGTATTGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCCTTTATTACAGGATGTACTCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAGATGTGAGTTGTTTGAAAATCGCTGGATAGGAACTCATCTAGCGGGTGCATCATTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTAGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCTTGGCAGCAAGAACAGCTTCTCGAAGCACTGGGTATTG
TTGTTTTTCCTGACTAG

>>MEG_6026|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAATCTACAGTCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6027|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGGTCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6028|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCATGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6029|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ACTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6030|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTTCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6031|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCACCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCGCTTTGATGTCGCAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA

>>MEG_6032|Drugs|Fluoroquinolones|Quinolone_resistance_protein_Qnr|QNRS
ATGGAAACCTACAATCATACATATCGGCACCACAACTTTTCACATAAAGACTTAAGTGATCTCACCTTCGCCGCTTGCAC
ATTCATTCGCAGCGACTTTCGACGTGCTAACTTGCGTGATACGACATTCGTCAACTGCAAGTTCATTGAACAGGGTGATA
TCGAAGGCTGCCACTTTGATGTCACAGATCTTCGTGATGCAAGTTTCCAACAATGCCAACTTGCGATGGCAAACTTCAGT
AATGCCAATTGCTACGGTATAGAGTTCCGTGCGTGTGATTTAAAAGGTGCCAACTTTTCCCGAACAAACTTTGCCCATCA
AGTGAGTAATCGTATGTACTTTTGCTCAGCATTTATTTCTGGATGTAATCTTTCCTATGCCAATATGGAGAGGGTTTGTT
TAGAAAAATGTGAGTTGTTTGAAAATCGCTGGATAGGAACGAACCTAGCGGGTGCATCACTGAAAGAGTCAGACTTAAGT
CGAGGTGTTTTTTCCGAAGATGTCTGGGGGCAATTTAGCCTACAGGGTGCCAATTTATGCCACGCCGAACTCGACGGTTT
AGATCCCCGCAAAGTCGATACATCAGGTATCAAAATTGCAGCCTGGCAGCAAGAACTGATTCTCGAAGCACTGGGTATTG
TTGTTTATCCTGACTAA