MEGAResFrom MEG, the Microbial Ecology Group

Fluoroquinolones

The fluoroquinolone class of antibiotics target the bacterial DNA topoisomerases II (gyrase) and IV, converting them into a product that is toxic to the bacterial cell. Common drugs in this class include ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, etc.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/24576155

Mechanisms

Sequences

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