MEGAResFrom MEG, the Microbial Ecology Group

phoP

The two-component system PhoP-PhoQ has been described as contributing to polymyxin B and multi-drug resistance through specific mutations.

References

Sequences

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>CARD|pvgb|AP009048|1191352-1192024|ARO:3003585|Klebsiella|Cationic_antimicrobial_peptides|Polymyxin-resistant_phoP|phoP|RequiresSNPConfirmation
TCAGCGCAATTCGAACAGATAGCCCTGGCCGCGAACGGTGGTAATCACTTCTTGGGGATATTGTGCCTGAATTTTTTTGC
GCAGACGTCCCATCAGTACATCAATGGTATGGCTTTCCCGCAGCTCCGCATCCGGATAGAGTTGGAGCATTAACGAATCT
TTGCTGACCACTTTGCCATTATTGCGTATCAACGTTTCCATAATAGTGTATTCGAACGCGGTCAGTTTGATCACTTCGTC
ATTAATAGATAATTCACGGCGAGAGAGATCAACCTGAAACGGGGGGAGCGAAATGACCTGTGAAGCCAGACCGCTATTAC
GCCGCATTAATGCCTGCATTCGCGCCATCACCTCTTCAATATGAAACGGTTTAGTCACATAATCATCAGCACCGGCACTT
AATACTTCGACTTTGTCCTGCCAGCTTTCACGGGCGGTTAATACCAGAATCGGCAGTGAAACATCGTTGCTACGCCAGCG
GCGAATCAGTGACAGACCGTCCTCGTCTGGCAATCCGAGATCGACAATCGCAATATCCGGTATATGTTCATTGAGATAAT
AATCGGCTTCTTTGGCATCTTCTGCGTCATCGACCTGATGACCAGCATCCTGAATCTGAACTTTAAGGTGGTGACGTAAC
AACGCATTGTCTTCAACAACCAGTACGCGCAT