MEGAResFrom MEG, the Microbial Ecology Group

Undecaprenyl pyrophosphate phosphatase

The BacA undecaprenol kinase can synthesize C55-isoprenyl phosphate and circumvent the biosynthesis pathway that bacitracin disrupts in its mechanism of action. This causes resistance via novel production of isoprenyl phosphate.

References

  • http://www.ncbi.nlm.nih.gov/pubmed/12399481

Other Mechanisms in Bacitracin

Groups

Sequences

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