MEGAResFrom MEG, the Microbial Ecology Group

APH9

Aminoglycoside O-phosphotransferases transfer a phosphate from ATP to a specific hydroxyl group on the aminoglycoside molecule. This confers resistance by drug modification. Aph(9) phosphotransferases modify the 9 hydroxyl group.

References

Other Groups in Aminoglycoside O-phosphotransferases

Sequences

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>AGly|aph9-Ib_1_U70376|Aminoglycosides|Aminoglycoside_O-phosphotransferases|APH9
TCAGCTCGGTACTTCGGAGTTCAGATGGTCGAGAGTCTCGGCGAAGCTCTGCCAAGCGGCTTCGGTGTCGGAGGTGCGCT
GGTGTTCCCCGCGGAACCACTCGACGAACTCGGCGACGTCCAGCAGGCTCCACCGCAGCCGGTAGAGCGCCAGCGCGGCC
GGGTCGGGCGTGTGCCCGGTCAGTTCGGTGTAGCGGGCGAGAGCTGCCGGGTCGTCCGAGATCAGGGAGAGGTCCCGTTC
GGGTATCGCGAGGCCCACCGTGTCCCAGTCCACCAGCACATAGCCGTCCTCACCAAGGATCAGGTTCCCCGGGTGCGGCT
CGCCGTGTGTGACGACCAGCGGGGCGCCGCGGCCCCGTACCCGCGCCACCAGTTCGCCGAACTCCGCCATCCGCCCGCGG
AGCGTCGCCTCGTGCTCGGCCAGCAACTCGCGGGCCGGCTCGGAGAACGGCCCGCCCGTCCAGGTTCCGGACGGCTCGGC
CAGCGCGGTGTGCACGCCATCCAGTCCGGTCGGCACCATGTCGGTGGTCGGGGTGCACTTCGGCGGTGCCTGGCCGTGCA
ATTCTGCGAGCAGCACCAGCACCTGGTCCCGCTCCCGCTCCGTCAGCTTCTGGCCGAACTCCCCGGGTCGGGCCGAGACA
TGGGGAAATACGGTCAACGCGTACCGCGAGTCCAGCGGGACCAGTGAAGCGCCGTCACTCGTGGTCCGGGGTGCCACCAC
GAACGGCAGGCCGCCCTGCTCACGCAAGTGCACCGCGGTGTCCATGGCTCTCCGCAGACCTCGCAGTGCCGCCGGGGCAC
CGTGCCCGCAGTGCTCCTTGTGTTCGAGGTCGGAGACGGTGGCGAACCACCGCTGCCCGTCGTCACCGGTGATGTGCCAG
TGATAGTCGCCGAAGCCGAGCGGCGCGTACGACGCACTGGTCGTGGAGATACCGAATTCTCGTAGTCCCTGAAATAGGCT
TTCCTGGTCCAGGTTCTCAGGAAGATCTTCCAT

>AGly|CR628337.1|gene1595|Aminoglycosides|Aminoglycoside_O-phosphotransferases|APH9
ATGCTAAGAAATAACATTCCGGATCAACACCTCATTGCGCTTTTGAAAGTCTATTATGGAATTGATATTCATACTGTACA
ACTCATCGTGGGTGGTGCTGATATGAATGCCTTTGGATATAAAGCGGATTCAGAATCCAATTCTTATTTCGTAAAGCTGA
AATACGGCCATCATGATGAAATTAATTTATCAATCATTCGCCTCTTGCATGATTCTGGAATAAAAGAAATTATTTTTCCT
ATCTACACACGTGATACAAAATTATTTCAGCAAATAGATCATTTTAAAATAATAGTGTATCCATTTATTAATGCGCCCAA
TGGCTTCACTCAAAATTTAACAGAAAAACAGTGGCACCAGCTTGGAAAAGTATTAAGACAAATTCATGAAACTTCTGTTC
CCACCGCTATTCAGCAACGATTAAGGAAAGAAACTTATTCGCCTAAATGGCGTGAAATGGTTAGATCTTTTTATAACAAA
ATTGGATTTGATGATTCAGATGATCAAATTACTACTGACTTCAAAACTTTTTTTAATCAAAATATCGATTCAATTCATCG
ATTAGTCGATTCTTCAGAAGAACTATCTAAAAAAATTCAACCCGATTTAGATAAATATGTACTGTGTCATTCTGATGTAC
ATGCGGGCAATGTATTGGTCGTTAATGAGGAATCTATTTACATTATTGATTGGGATGAGCCCATGTTAGCGCCAAAAGAG
TGTGATTTGATGTTCATTGGCGGTGGCATTGGTAATGTATGGAATAAACACCATGAAATCAATTATTTTTATGAAGGTTA
TGGTAAAACAAACGTTGATAAAATAATTTTATCTTATTACAGACATGAACGAATTGTCGAAGATATAGCTGTATATGGAC
AAGACTTACTTTCACGTGATCAAAACGACGAGTCCAGACTTGAAAGTTTTAAACATTTTAAATCGATGTTTACTCCAAAT
GATGTTGTTGAAATAGCTTTTTCTTCGGATTAA

>AGly|Aph9-Ia|U94857|151-1146|996|Aminoglycosides|Aminoglycoside_O-phosphotransferases|APH9
ATGCTAAAACAACCAATTCAAGCTCAACAACTTATCGAACTTTTGAAAGTGCATTATGGAATTGATATTCATACAGCACA
ATTCATCCAGGGTGGTGCTGATACGAATGCATTTGCATATCAAGCAGATTCAGAATCCAAGTCTTATTTCATAAAGCTAA
AATACGGCTATCATGATGAAATTAATTTATCGATAATCCGTCTTTTACATGATTCTGGAATAAAAGAAATTATTTTTCCT
ATCCATACACTTGAAGCAAAATTATTCCAGCAACTAAAGCATTTTAAAATAATTGCGTATCCATTTATTCATGCGCCCAA
TGGTTTCACCCAAAATTTAACAGGAAAACAGTGGAAACAGCTTGGAAAAGTATTAAGACAAATTCATGAAACATCAGTTC
CCATCTCGATTCAACAACAATTAAGAAAAGAAATATACTCCCCTAAATGGCGTGAAATAGTCAGATCCTTTTATAATCAA
ATTGAATTTGATAATTCAGATGATAAGCTCACGGCTGCCTTTAAATCTTTTTTTAACCAAAATAGTGCTGCAATTCATCG
ATTAGTTGATACTTCAGAAAAACTATCTAAAAAAATTCAACCTGATTTAGATAAATACGTACTATGTCATTCTGATATAC
ATGCGGGCAATGTGTTAGTCGGTAATGAAGAGTCGATTTACATTATTGATTGGGATGAGCCTATGTTAGCTCCAAAAGAA
CGTGATTTGATGTTCATAGGTGGTGGCGTTGGTAATGTATGGAATAAACCCCATGAAATCCAATATTTTTATGAAGGTTA
TGGTGAAATAAATGTCGATAAAACAATTTTGTCTTATTACAGGCATGAACGAATTGTCGAAGATATCGCAGTATACGGGC
AAGACTTGCTTTCACGTAATCAAAACAATCAGTCCAGACTTGAAAGTTTTAAATATTTTAAAGAAATGTTTGATCCAAAC
AACGTTGTTGAAATAGCTTTTGCTACAGAGCAGTAA