MEGAResFrom MEG, the Microbial Ecology Group

APH6-PRIME

Aminoglycoside O-phosphotransferases transfer a phosphate from ATP to a specific hydroxyl group on the aminoglycoside molecule. This confers resistance by drug modification. Aph(6') phosphotransferases modify the 6 prime hydroxyl group.

References

Other Groups in Aminoglycoside O-phosphotransferases

Sequences

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>926|AF337947.1|AF337947|Aminoglycosides|Aminoglycoside_O-phosphotransferases|APH6-PRIME
ATGTTGGAAAAAAAGCGAGTTTCCTTTCGCCCGATGAATGAGGATGATTTAGTTCTAATGTTAAAATGGCTGACAGATGA
CCGTGTTCTTGAATTCTACGACGGTAGAGATAAAAAACATACACAGAAAACGATTCGTGAGCATTATACAGAGCAATGGG
CGGATGAGATTTATCGAGTCATCATTGAATATGATACAATTCCTATCGGTTACGCACAAATATATAGAATTCAGGGGGAA
CTTTTCGACGAATATAATTACCATGAGACGGAAGAAAAGATTTATGCGATGGACCAATTTATCGGTGAGCCGGAATATTG
GAATATGGGAATCGGTGCAGAATATTGCAGAGTAGTATGCCAATATCTACGAACGGAAATGGATGCCGATGCGGTGATTC
TTGACCCACGAAAAAATAATCTACGAGCAGTACGAGCATATCAGAAGGCAGGATTTAAAATAATTAAGGAACTTCCCGAA
CATGAGCTACACGAGGGGAAAAAGGAAGATTGTGTGCTGATGGAATGGAGAGTGTAA