MEGAResFrom MEG, the Microbial Ecology Group

Aminoglycoside O-nucleotidyltransferases

Resistance to aminoglycosides is commonly caused by modification of the drug itself via O-phosphoylation, O-nucleotidylation, and N-acetylation. Aminoglycoside O-nucleotidyltransferases transfer a nucleoside triphosphate to the aminoglycoside, which results in resistance by drug modification. Other common names for this type of aminoglycoside modifying enzyme include adenyltransferase, and adenylyltransferase.

References

Other Mechanisms in Aminoglycosides

Groups

Sequences

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