MEGAResFrom MEG, the Microbial Ecology Group

AAC2-PRIME

Aminoglycoside N-acetyltransferases modify a specific amino group on the aminoglycoside molecule by transferring an acetyl group from acetyl-CoA to the aminoglycoside drug; the type of N-acetyltransferase is named after which amino group it modifies. AAC(2') aminoglycosides modify the 2 prime amino group.

References

Other Groups in Aminoglycoside N-acetyltransferases

Sequences

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>859|U41471.1|MFU41471|Aminoglycosides|Aminoglycoside_N-acetyltransferases|AAC2-PRIME
GTGCCTTTCCAGGATGTCAGCGCGCCCGTTCGAGGCGGGATCCTGCACACCGCTCGACTCGTCCACACCTCCGATCTCGA
TCAGGAGACTCGAGAGGGCGCCCGCCGCATGGTCATCGAGGCGTTCGAGGGTGATTTCAGCGACGCCGACTGGGAGCACG
CGCTCGGTGGCATGCACGCCTTCATCTGTCACCACGGCGCTCTGATCGCGCATGCCGCGGTGGTCCAGCGCCGGCTGCTC
TACCGCGACACCGCGCTGCGCTGCGGGTACGTGGAAGCCGTGGCGGTGCGCGAAGATTGGCGCGGCCAAGGCCTGGCCAC
CGCCGTCATGGACGCGGTCGAACAGGTGCTGCGCGGCGCCTACCAGCTCGGCGCCCTCAGTGCGTCCGACACAGCCAGAG
GCATGTACCTCTCTCGCGGGTGGCTGCCGTGGCAGGGGCCGACCTCGGTGCTGCAGCCGGCCGGCGTGACGCGTACACCC
GAGGACGACGAGGGACTGTTCGTGCTGCCCGTCGGTCTCCCGGCGGGAATGGAACTCGACACCACAGCCGAGATCACCTG
CGACTGGCGCGACGGGGACGTCTGGTAA

>921|U72714.1|MTU72714|Aminoglycosides|Aminoglycoside_N-acetyltransferases|AAC2-PRIME
GTGCACACCCAGGTACACACGGCCCGCCTGGTCCACACCGCCGATCTTGACAGCGAGACCCGCCAGGACATCCGTCAGAT
GGTCACCGGCGCGTTTGCCGGTGACTTCACCGAGACCGACTGGGAGCACACGCTGGGTGGGATGCACGCCCTGATCTGGC
ATCACGGGGCGATCATCGCGCATGCCGCGGTGATCCAGCGGCGACTGATCTACCGCGGCAACGCGCTGCGCTGCGGGTAC
GTCGAAGGCGTTGCGGTGCGGGCGGACTGGCGGGGCCAACGCCTGGTGAGCGCGCTGTTGGACGCCGTCGAGCAGGTGAT
GCGCGGCGCTTACCAGCTCGGAGCGCTCAGTTCCTCGGCGCGGGCCCGCAGACTGTACGCCTCACGCGGCTGGCTGCCCT
GGCACGGCCCGACATCGGTACTGGCACCAACCGGTCCAGTCCGTACACCCGATGACGACGGAACGGTGTTCGTCCTGCCC
ATCGACATCAGCCTGGACACCTCGGCGGAGCTGATGTGCGATTGGCGCGCGGGCGACGTCTGGTAA

>AGly|Aac2-Ie|NC_011896|3039059-3039607|549|Aminoglycosides|Aminoglycoside_N-acetyltransferases|AAC2-PRIME
ATGGATACCCACCACGTACATACCGCCCGCCTGGTTCATACCGCCGATCTCGACGGCGAGACTCTCCGGCGCCTCCAGCA
GATGGTCACCGACGCTTTCGCCGGAGACTTCGACGAGACCGACTGGGAACACGCATTGGGCGGGATGCACGCCCTGATCT
GGCGGCACGGCACAATCATTGCGCACGCCGCGGTCGTTCAGCGGCGACTATTCTACCACGGCAACGCGTTGCGTTGCGGT
TACCTCGAAGGTGTCGCGGTACGGAAGGACTGCCGGGGCCGCGGACTTGTACATGCGCTGCTGGACGCTATCGAGCAAGT
GATACGCGGCGCCTATCAATTCGGTGCCTTGAGTTCCTCGGACCGAGCCCGTCGGGTGTATATGTCGCGCGGGTGGTTAC
CATGGCTCGGCCCGACGTCAGTGCTGGCTCCTACCGGTGTGATCCGTACGCCCGATGATGACGGCTCGGTGTTTGTCCTT
CCGGTCGGCATCAACCCGGACACCTCCTCGGGGTTGATGTGCGATTGGCGCGCAGGCAACGTGTGGTAA

>CARD|phgb|AL123456|314308-314854|ARO:3002525|AAC2-PRIME-Ic|Aminoglycosides|Aminoglycoside_N-acetyltransferases|AAC2-PRIME
TTACCAGACGTCGCCCGCGCGCCAATCGCACATCAGCTCCGCCGAGGTGTCCAGGCTGATGTCGATGGGCAGGACGAACA
CCGTTCCGTCGTCATCGGGTGTACGGACTGGACCGGTTGGTGCCAGTACCGATGTCGGGCCGTGCCAGGGCAGCCAGCCG
CGTGAGGCGTACAGTCTGCGGGCCCGCGCCGAGGAACTGAGCGCTCCGAGCTGGTAAGCGCCGCGCATCACCTGCTCGAC
GGCGTCCAACAGCGCGCTCACCAGGCGTTGGCCCCGCCAGTCCGCCCGCACCGCAACGCCTTCGACGTACCCGCAGCGCA
GCGCGTTGCCGCGGTAGATCAGTCGCCGCTGGATCACCGCGGCATGCGCGATGATCGCCCCGTGATGCCAGATCAGGGCG
TGCATCCCACCCAGCGTGTGCTCCCAGTCGGTCTCGGTGAAGTCACCGGCAAACGCGCCGGTGACCATCTGACGGATGTC
CTGGCGGGTCTCGCTGTCAAGATCGGCGGTGTGGACCAGGCGGGCCGTGTGTACCTGGGTGTGCACA

>826|U72743.1|MSU72743|Aminoglycosides|Aminoglycoside_N-acetyltransferases|AAC2-PRIME
GTGCTCACCCAGCATGTCAGTGAGGCTCGCACGCGCGGTGCGATCCACACCGCGCGTCTGATCCACACCTCCGATCTGGA
CCAGGAAACCCGCGACGGCGCGCGCCGCATGGTGATCGAGGCGTTCCGCGATCCGTCCGGAGACAGTGATTTCACCGACG
ATTTCACCGACGACGACTGGGACCACGCGCTCGGCGGCATGCACGCGCTGATCTCTCACCACGGTGCGCTCATCGCGCAC
GGCGCCGTCGTCCAACGTCGGTTGATGTACCGGGGACCCGACGGTAGAGGTCACGCGCTGCGCTGCGGTTACGTCGAGGC
CGTCGCGGTGCGCGAGGACCGGCGGGGCGACGGTCTGGGCACCGCCGTGCTCGACGCGCTCGAGCAGGTGATCCGCGGCG
CCTATCAGATCGGCGCGCTGAGCGCGTCGGACATCGCCCGGCCGATGTACATTGCCAGGGGCTGGCTGTCGTGGGAGGGT
CCGACATCGGTGCTGACCCCCACCGAGGGCATCGTTCGCACCCCTGAGGACGACCGGTCGCTGTTCGTCCTGCCGGTCGA
TCTCCCGGACGGCCTCGAGTTGGACACCGCGCGCGAGATCACGTGCGACTGGCGCTCCGGCGACCCCTGGTGA

>858|L06156.1|PROAAC2IA|Aminoglycosides|Aminoglycoside_N-acetyltransferases|AAC2-PRIME
ATGGGCATAGAATACCGCAGTCTGCATACCAGCCAATTGACACTGAGTGAAAAAGAAGCGCTTTACGATTTATTAATTGA
AGGTTTTGAAGGCGATTTTTCGCATGACGATTTCGCGCACACTTTAGGTGGAATGCACGTCATGGCTTTTGATCAACAAA
AATTGGTTGGTCATGTTGCAATTATTCAACGCCATATGGCCCTAGATAATACGCCTATCTCTGTAGGGTATGTTGAAGCG
ATGGTAGTTGAACAAAGTTATCGTCGCCAAGGTATTGGGCGGCAATTGATGCTGCAAACCAATAAAATTATAGCTTCGTG
TTATCAATTAGGGCTGCTGTCGGCTTCAGATGATGGACAAAAATTGTATCATTCGGTTGGATGGCAAATCTGGAAAGGTA
AGTTGTTTGAATTGAAACAAGGGAGCTATATCCGTTCTATTGAAGAAGAAGGCGGAGTCATGGGCTGGAAAGCGGATGGT
GAGGTTGATTTTACCGCTTCGCTTTACTGTGATTTTCGTGGCGGTGATCAGTGGTAA