MEGAResFrom MEG, the Microbial Ecology Group

Aminoglycoside N-acetyltransferases

Resistance to aminoglycosides is commonly caused by modification of the drug itself via O-phosphoylation, O-nucleotidylation, and N-acetylation. Aminoglycoside N-acetyltransferases modify a specific amine group on the aminoglycoside molecule by transferring an acetyl group from acetyl-CoA to the aminoglycoside drug; the group of N-acetyltransferase is named after which amine group it modifies.


Other Mechanisms in Aminoglycosides



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