MEGAResFrom MEG, the Microbial Ecology Group

Aminoglycoside-resistant 30S ribosomal subunit protein S12

Mutations in the S12 protein, which is part of the 30S ribosomal subunit, or in homologous regions in the 16S rRNA of the 30S ribosomal subunit confer resistance to streptomycin via the modification of the ribosomal component. This modification reduces drug binding affinity.


Other Mechanisms in Aminoglycosides



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