MEGAResFrom MEG, the Microbial Ecology Group

Aminoglycoside-resistance regulator mutation

Resistance to aminoglycoside antibiotics can be conferred via overexpression of the MexXY-OprM efflux pump. This has been described via loss-of-function mutations in the MexZ gene, which is a repressor of the mexXY operon, resulting in overexpression of the pump.

References

Other Mechanisms in Aminoglycosides

Groups

Sequences

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